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28,711 results
  • Targeted metabolomics to investigate antimicrobial activity of itaconic acid in marine molluscs. [Journal Article]
  • MMetabolomics 2019 Jun 22; 15(7):97
  • Van Nguyen T, Alfaro AC
  • CONCLUSIONS: We reported on the production of ITA in different tissues of P. canaliculus mussels challenged with a marine pathogen which confirmed ITA as an antimicrobial metabolite. The findings revealed insights into the biosynthesis of ITA and suggests its role in antimicrobial and anti-inflammatory activities in the innate immune system. This study also provided insights into the innate immune system of bivalves and highlighted the potential use of ITA as a biomarker for shellfish health assessment in aquaculture.
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