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Unbound Medicine.
(World Health Organization)
142,574 results
  • Designing molecular diagnostics for current tuberculosis drug regimens. [Journal Article]
    Emerg Microbes Infect. 2023 Feb 08 [Online ahead of print]Georghiou SB, de Vos M, … Ruhwald M
  • Diagnostic development must occur in parallel with drug development to ensure the longevity of new treatment compounds. Despite an increasing number of novel and repurposed anti-tuberculosis compounds and regimens, there remains a large number of drugs for which no rapid and accurate molecular diagnostic option exists. The lack of rapid drug susceptibility testing for linezolid, bedaquiline, clof…
  • Monkeypox: a review of the 2022 outbreak. [Journal Article]
    Br Med Bull. 2023 Feb 06 [Online ahead of print]Lim EY, Whitehorn J, Rivett L
  • CONCLUSIONS: The higher numbers of HIV-positive patients in the current outbreak has allowed better description of the disease in patients co-infected with HIV and monkeypox. The absence of more severe symptoms in HIV-positive patients in the current outbreak could possibly be due to the fact that most of these patients had well-controlled HIV, although further characterization of this cohort of patients would be useful.Current treatment and vaccination options have been extrapolated from studies of other Orthopox viruses. There remains a need for more data on the safety and efficacy of these options in the context of monkeypox infections.
  • Age, geographical and socio-economic related inequalities in contraceptive prevalence: evidence from the 1993-2014 Ghana Demographic and Health Surveys. [Journal Article]
    Contracept Reprod Med. 2023 Feb 07; 8(1):20.Mensah F, Okyere J, … Ahinkorah BO
  • CONCLUSIONS: There was a steady increase in contraceptive use from 20.3% in 1993 to 26.7% in 2014. Nevertheless, the percentage change is minimal. The trends of inequality indicate that inequalities in contraceptive use was evident across the dimension of age, place of residence, wealth index, education, and region. Yet, there was a substantial reduction in inequalities related to contraceptive use in 2014. Therefore, targeting adolescents, women in rural areas, low wealth quintile, and those with no formal education is key to substantially improving contraceptive use across the country.
  • Optimal spatial evaluation of a pro rata vaccine distribution rule for COVID-19. [Journal Article]
    Sci Rep. 2023 Feb 07; 13(1):2194.Castonguay FM, Blackwood JC, … Sanchirico JN
  • The COVID-19 Vaccines Global Access (COVAX) is a World Health Organization (WHO) initiative that aims for an equitable access of COVID-19 vaccines. Despite potential heterogeneous infection levels across a country, countries receiving allotments of vaccines may follow WHO's allocation guidelines and distribute vaccines based on a jurisdictions' relative population size. Utilizing economic-epidemi…
  • Monkeypox-induced proctitis: a case report of an emerging complication. [Journal Article]
    Infection. 2023 Feb 07 [Online ahead of print]Rathore A, Kahn C, … House JG
  • CONCLUSIONS: As more cases of monkeypox-associated proctitis emerge, clinicians should keep this disease in their differential due to the growing atypical presentations that have diverged from previous patterns to avoid the risk of misdiagnosing another sexually transmitted infection. Additionally, appropriate medical management is still not definitive and requires further development of evidence-based protocols to treat such patients.
  • What's in a name? Unpacking 'Community Blank' terminology in reproductive, maternal, newborn and child health: a scoping review. [Journal Article]
    BMJ Glob Health. 2023 Feb; 8(2)Dada S, Cocoman O, … Gilmore B
  • CONCLUSIONS: Across the literature, there is inconsistency in the usage of 'community blank' terms for RMNCH. There is an observed interchangeable use of terms and a lack of descriptions of these terms provided in the literature. There is a need for RMNCH researchers and practitioners to clarify the descriptions reported and improve the documentation of 'community blank' implementation. This can contribute to a better sharing of learning within and across communities and to bringing evidence-based practices to scale. Efforts to improve reporting can be supported with the use of standardised monitoring and evaluation processes and indicators. Therefore, it is recommended that future research endeavours clarify the operational definitions of 'community blank' and improve the documentation of its implementation.
  • An Integrated Review of Obstetric Admissions in the Intensive Care Unit. [Journal Article]
    Dimens Crit Care Nurs. 2022 May-Jun 01; 41(3):132-143.Luebcke C, Smith BE, Abrahamson K
  • CONCLUSIONS: This review provided information on characteristics of the obstetric critical care population. Education and instituting early warning systems, formal debriefings, and standardization of protocols may assist in preparing critical care nurses in confidently caring for this population.
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