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79,010 results
  • The ethics of sensor technology use in clinical research. [Journal Article]
    Nurs Outlook. 2020 Jul 01 [Online ahead of print]Ulrich CM, Demiris G, … Rothwell E
  • CONCLUSIONS: Balancing the benefits with the potential risks of advanced information technology will require ethically astute researchers who can address the challenges that might arise while advancing knowledge with innovation that can improve the lives of patients and families.
  • Methods of estimation of pleural effusion by ecography. [Review]
    Rev Esp Anestesiol Reanim. 2020 May 15 [Online ahead of print]Carvajal Revuelta E, García Álvarez R
  • Pleural effusion is a frequent pathology in intensive care units. The diagnosis has improved after the introduction of pulmonary ultrasound, an accessible method at the bedside, which allows not only the diagnosis but also the treatment of this entity. The aim of our study is to determine the accuracy of published mathematical equations to calculate the volume of pleural effusion from ultrasound …
  • Multiscale ATUM-FIB Microscopy Enables Targeted Ultrastructural Analysis at Isotropic Resolution. [Journal Article]
    iScience. 2020 Jun 20; 23(7):101290.Kislinger G, Gnägi H, … Schifferer M
  • Volume electron microscopy enables the ultrastructural analysis of biological tissue. Currently, the techniques involving ultramicrotomy (ATUM, ssTEM) allow large fields of view but afford only limited z-resolution, whereas ion beam-milling approaches (FIB-SEM) yield isotropic voxels but are restricted in volume size. Now we present a hybrid method, named ATUM-FIB, which combines the advantages o…
  • Attentional flexibility and prioritization improves long-term memory. [Journal Article]
    Acta Psychol (Amst). 2020 Jul 01; 208:103104.Sandry J, Zuppichini MD, Ricker TJ
  • Recent evidence suggests the focus of attention (FoA) is a flexible resource within working memory (WM) used to temporarily maintain some information in a highly accessible state. This flexibility comes at the expense of other representations, demonstrating a resource trade-off in WM maintenance. The present experiments evaluate how flexibility within the FoA impacts long-term memory (LTM) for se…
  • SAGER: a database of Symbiodiniaceae and Algal Genomic Resource. [Journal Article]
    Database (Oxford). 2020 Jan 01; 2020Yu L, Li T, … Lin S
  • Symbiodiniaceae dinoflagellates are essential endosymbionts of reef building corals and some other invertebrates. Information of their genome structure and function is critical for understanding coral symbiosis and bleaching. With the rapid development of sequencing technology, genome draft assemblies of several Symbiodiniaceae species and diverse marine algal genomes have become publicly availab…
  • Modeling Protein Homo-Oligomer Structures with GalaxyHomomer Web Server. [Journal Article]
    Methods Mol Biol. 2020; 2165:127-137.Baek M, Park T, … Seok C
  • Cellular processes, such as metabolism, signal transduction, or immunity, often depend on the homo-oligomerization of proteins. Detailed structural knowledge of the homo-oligomer structure is therefore crucial for molecular-level understanding of protein functions and their regulation. In this chapter, we introduce the GalaxyHomomer server, which supports easy-to-use web interfaces for general us…
  • Single-cell ATAC-seq signal extraction and enhancement with SCATE. [Journal Article]
    Genome Biol. 2020 Jul 03; 21(1):161.Ji Z, Zhou W, … Ji H
  • Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in single cells. Single-cell ATAC-seq data are sparse and noisy, and analyzing such data is challenging. Existing computational methods cannot accurately reconstruct activities of individual cis-regulatory elements (CREs) in individual c…
  • A review: accessible technology through participatory design. [Journal Article]
    Disabil Rehabil Assist Technol. 2020 Jul 03 [Online ahead of print]Quintero C
  • Purpose: The literature review presents a conceptual participatory design through accessibility technology solutions, considering the design experience to be an essential factor in communication processes. Technologies must assess a wide range of disabilities based on characterisations that helps daily activities. This work includes collaboration concepts to assist in the development of accessib…
  • From Raw Data to FAIR Data: The FAIRification Workflow for Health Research. [Journal Article]
    Methods Inf Med. 2020 Jun; 59(S 01):e21-e32.Sinaci AA, Núñez-Benjumea FJ, … Parra-Calderón CL
  • CONCLUSIONS:  Research funding agencies all over the world increasingly demand the application of the FAIR guiding principles to health research output. Existing tools do not fully address the identified needs for health data management. Therefore, researchers may benefit in the coming years from a common framework that supports the proposed FAIRification workflow applied to health datasets. Routine health care datasets or data resulting from health research can be FAIRified, shared and reused within the health research community following the proposed FAIRification workflow and implementing technical architecture.
  • Exchange of Clinical and Omics Data According to FAIR Principles: A Review of Open Source Solutions. [Journal Article]
    Methods Inf Med. 2020 Jun; 59(S 01):e13-e20.Pugliese P, Knell C, Christoph J
  • CONCLUSIONS:  There are already platforms in the translational environment that take FAIR principles into account and thus improve translational research. Due to the specialization of the research platforms and the fact that FAIR are only principles and not standards, the platforms have to be examined in individual cases to see whether and how they can be integrated with other platforms.
  • CORDITE: The Curated CORona Drug InTERactions Database for SARS-CoV-2. [Journal Article]
    iScience. 2020 Jun 20; 23(7):101297.Martin R, Löchel HF, … Heider D
  • Since the outbreak in 2019, researchers are trying to find effective drugs against the SARS-CoV-2 virus based on de novo drug design and drug repurposing. The former approach is very time consuming and needs extensive testing in humans, whereas drug repurposing is more promising, as the drugs have already been tested for side effects, etc. At present, there is no treatment for COVID-19 that is cl…
  • The Efficacy of Binaural Beats as a Stress-buffering Technique. [Journal Article]
    Altern Ther Health Med. 2020 Jul 01 [Online ahead of print]Kelton K, Weaver TL, … Santowski A
  • CONCLUSIONS: The current study found that the intervention group, who listened to TBBs, had greater parasympathetic dominance during TSST than the control group. This suggests that TBB exposure may dampen subsequent stress responses to an acute, psychological stressor. This finding, however, should be interpreted with caution, because further research and independent replication are warranted.
  • The role of FLIR ONE ® thermography in complex regional pain syndrome: A case series. [Journal Article]
    Am J Phys Med Rehabil. 2020 Jul 01 [Online ahead of print]Dhatt S, Winston P
  • Complex regional pain syndrome (CRPS) remains a debated syndrome characterized by symptoms and signs, including pain, sensory disturbances, thermal asymmetry, edema, and motor impairments. Thermography is a tool that assesses skin surface temperature distribution. Current literature appears to support the role of thermography for diagnostic purposes, however its role in monitoring the response to…
  • Prognostic tools for hypertrophic scar formation based on fundamental differences in systemic immunity. [Journal Article]
    Exp Dermatol. 2020 Jul 03 [Online ahead of print]de Bakker E, van der Putten MA, … Gibbs S
  • Unpredictable hypertrophic scarring (HS) occurs after approximately 35% of all surgical procedures and causes significant physical and psychological complaints. Parallel to the need to understanding the mechanisms underlying HS formation, a prognostic tool is needed. The objective was to determine whether (systemic) immunological differences exist between patients who develop HS and those who dev…
  • Vestigial auriculomotor activity indicates the direction of auditory attention in humans. [Journal Article]
    Elife. 2020 Jul 03; 9Strauss DJ, Corona-Strauss FI, … Hackley SA
  • Unlike dogs and cats, people do not point their ears as they focus attention on novel, salient, or task-relevant stimuli. Our species may nevertheless have retained a vestigial pinna-orienting system that has persisted as a 'neural fossil' within in the brain for about 25 million years. Consistent with this hypothesis, we demonstrate that the direction of auditory attention is reflected in sustai…
  • Bovine peripheral blood MSCs chemotax towards inflammation and embryo implantation stimuli. [Journal Article]
    J Cell Physiol. 2020 Jul 02 [Online ahead of print]Calle A, Gutiérrez-Reinoso MÁ, … Ramírez MÁ
  • Mesenchymal stem cells (MSCs) have a great potential in regenerative medicine because of their multipotential and immunoregulatory capacities, while in early pregnancy they could participate in the immunotolerance of the mother towards the embryo. Peripheral blood constitutes an accessible source of MSCs. We successfully isolated peripheral blood MSC (pbMSCs) lines, with or without previous bone …
  • Cinematic rendering enhancements to virtual bronchoscopy: assessment of emergent tracheal pathology. [Journal Article]
    Emerg Radiol. 2020 Jul 02 [Online ahead of print]Lin CT, Rowe S, … Fishman EK
  • Utilizing complex lighting models, cinematic rendering is a novel technique for demonstrating computed tomography data with exquisite 3D anatomic detail. The tracheal lumen, tracheal wall, and adjacent soft tissue structures are represented with photorealistic detail exceeding that of conventional volume rendering or virtual bronchoscopy techniques. We applied cinematic rendering to a spectrum of…
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