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1,665 results
  • [Acral melanoma in a patient with hereditary keratoderma of the palms and soles (mal de Meleda): A chance association?] [Journal Article]
    Ann Dermatol Venereol 2019Korbi M, Hickman G, … Bourrat E
  • CONCLUSIONS: Mal de Meleda is a hereditary palmoplantar keratoderma due to mutation of the SLURP1 gene. Clinical diagnosis is based on the typical phenotype in adulthood. The occurrence of acral melanoma, which is a rare form of melanoma (1 to 7%), especially in the fingers, together with an unusual palmoplantar keratoderma in a subject of type IV phototype does not appear to be a chance event. This association seems to be the outcome of immune dysregulation rather than of chronic inflammation.
  • Combination Use of Systemic Therapies in Psoriasis: Baseline Characteristics from the Corrona Psoriasis Registry [Journal Article]
    J Drugs Dermatol 2019; 18(8):731-740Bonomo L, Abittan BJ, … Lebwohl M
  • CONCLUSIONS: Various demographic and socioeconomic factors are associated with use of combination systemic therapy compared to use of systemic monotherapy for psoriasis. An association with commonly used disease severity indices was not observed. RELEVANCE: An understanding of which patients are more likely to be prescribed combination systemic therapy will provide important context for long-term efficacy and safety data as they become available.
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