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2,034 results
  • Biological and immunosuppressive medications in pregnancy, breastfeeding and fertility in immune mediated diseases. [Review]
    Farm Hosp. 2023 Jan 27 [Online ahead of print]Ibarra Barrueta O, García Martín E, … Ais Larisgoitia A
  • CONCLUSIONS: In this context of chronic treatments with teratogenic potential, it is necessary to highlight the importance of pregnancy planning to select the safest drug. Given the quality of the available data, it is still necessary to continuously update the information, as well as to promote observational studies of cohorts of pregnant patients and men of childbearing age, including prospective studies, in order to generate more scientific evidence.
  • Case report: Infantile generalized pustular psoriasis with IL36RN and CARD14 gene mutations. [Case Reports]
    Front Genet. 2022; 13:1035037.Tong X, Li Y, … Liu S
  • Infantile pustular psoriasis (IPP) is an extremely rare skin disease associated with genetic factors. Gene mutations of IL36RN (interleukin-36 receptor antagonist), CARD14 (caspase recruitment family member 14), and AP1S1 (the σ1C subunit of the adaptor protein complex 1) had been identified to be involved in the pathogenesis of IPP. IPP usually develops with no preceding psoriasis vulgaris (PV) …
  • Netherton syndrome in a Bulgarian patient : Presentation of a case and an update of therapeutic options. [Journal Article]
    Wien Med Wochenschr. 2023 Jan 25 [Online ahead of print]Kordeva SA, Batashki I, Tchernev G
  • Comel-Netherton syndrome, or Netherton syndrome (NS), is a rare chronic genetic skin condition affecting the daily life of patients, which often results in poorly developed social skills and anxiety. Genetic predisposition plays a key role alongside the clinical findings, and clinicians must be aware of it as it can mimic other well-known skin conditions. Diagnosis is challenging both clinically …
  • Liver Disease Among Patients with Psoriasis: The Malaysian Psoriasis Registry. [Journal Article]
    Clin Exp Dermatol. 2023 Jan 12 [Online ahead of print]Lim YT, Robinson S, … Malaysian Psoriasis Registry Working Group
  • CONCLUSIONS: The frequency of psoriasis patients with liver disease in MPR was 0.8%. Psoriasis patients with liver disease were more likely to be male, had a higher rate of co-morbidities, severe disease, nail and joint involvement than those without liver disease.
  • Pityriasis Rubra Pilaris After Moderna COVID-19 Vaccination: A Case Report and Literature Review. [Journal Article]
    Am J Dermatopathol. 2023 Jan 10 [Online ahead of print]Liu YA, Dai J, … Cho WC
  • To date, over 60% of the world's population has received at least 1 dose of coronavirus disease 2019 (COVID-19) vaccination, with over 12 billion doses administered globally. Commonly reported adverse effects of COVID-19 vaccination include fever, headache, myalgia, and injection site reactions. The spectrum of documented cutaneous reactions after COVID-19 vaccination is broad; however, pityriasi…
  • Interleukin-17A Inhibitor Secukinumab Treatment in HIV-Positive Psoriasis Patient: A Case Report. [Case Reports]
    Clin Cosmet Investig Dermatol. 2022; 15:2949-2956.Gong J, Wu W, … Hu F
  • Psoriasis is an immune-mediated chronic inflammatory dermatosis influenced by hereditary and environmental factors. Human immunodeficiency virus (HIV) infection affects the immune system and exacerbates psoriatic lesions. We report the case of a 33-year-old male patient diagnosed with psoriasis vulgaris, psoriatic arthritis and HIV infection. Acitretin capsules, etanercept and high-active antiret…
  • Current treatments and emerging therapies of human polyomavirus-associated skin diseases: a comprehensive review. [Review]
    Int J Dermatol. 2022 Dec 28 [Online ahead of print]Bartley BR, Moore SA, … Tyring SK
  • Since Merkel cell polyomavirus (MCPyV) was linked as the predominant etiology of Merkel cell carcinoma (MCC) in 2008, three additional human polyomaviruses (HPyV) have been definitively linked to cutaneous diseases-trichodysplasia spinulosa virus (TSPyV) and human polyomavirus 6 and 7 (HPyV6, HPyV7). TSPyV contributes to the development of trichodysplasia spinulosa (TS), and HPyV6/7 is associated…
  • Successful Treatment of Severe Subcorneal Pustular Dermatosis with Adalimumab. [Case Reports]
    Clin Cosmet Investig Dermatol. 2022; 15:2567-2570.Chen J, Luo Y, … Zhu H
  • Subcorneal pustular dermatosis (SPD) is a rare, chronic pustular dermatosis. The pathogenesis of SPD has not been fully elucidated, but some studies have found that tumor necrosis factor (TNF)-α may be associated with its pathogenesis. Some patients with multidrug-resistant SPD have improved significantly after treatment with the anti-TNF-α agent (adalimumab). We present a case of a 28-year-old f…
  • An analysis of psoriasis hospitalisation in Thailand. [Journal Article]
    Arch Dermatol Res. 2022 Oct 29 [Online ahead of print]Chaiyabutr C, Silpa-Archa N, … Chularojanamontri L
  • Psoriasis hospitalisation is not frequently reported. The objective of this study was to determine (1) the clinical, laboratory and treatment features of patients with psoriasis hospitalised due to flare-up and (2) other causes of admission of patients with psoriasis. We retrospectively reviewed data on 48 patients admitted due to psoriasis flare-up and 1908 patients with psoriasis admitted due t…
  • The Use of Retinoids for the Prevention and Treatment of Skin Cancers: An Updated Review. [Review]
    Int J Mol Sci. 2022 Oct 20; 23(20)Ramchatesingh B, Martínez Villarreal A, … Litvinov IV
  • Retinoids are natural and synthetic vitamin A derivatives that are effective for the prevention and the treatment of non-melanoma skin cancers (NMSC). NMSCs constitute a heterogenous group of non-melanocyte-derived skin cancers that impose substantial burdens on patients and healthcare systems. They include entities such as basal cell carcinoma and cutaneous squamous cell carcinoma (collectively …
  • Retinoid-associated myopia in dermatologic patients: a systematic review. [Case Reports]
    Cutan Ocul Toxicol. 2022 Dec; 41(4):318-322.Roccuzzo G, Tibaldi T, … Ribero S
  • CONCLUSIONS: Considering the current literature, it is not possible to define a clear correlation between the use of retinoids and the development or worsening of myopia. Some studies suggest that retinoids may cause a myopic shift and the pathophysiologyical mechanism is supported by some animal and in vitro studies, but there is a lack of large prospective and well-controlled studies. In case of ocular disturbances after retinoid use a prompt ophthalmological referral is advisable and in case of the detection of a myopic refractive error a relationship to retinoids should be ruled out, considering also other possible causes such as age and previous refractive status.
  • Multiple keratoacanthomas of Ferguson-Smith type. [Case Reports]
    Clin Case Rep. 2022 Oct; 10(10):e06429.Litaiem N, Khammouma F, … Zeglaoui F
  • We report a case of a 41-year-old male patient with no family history, presented with extensive multiple keratoacanthomas with disfiguring scars. The diagnosis of a sporadic form of Ferguson-Smith syndrome was made. Treatment with acitretin showed a marked response. Recognizing this syndrome is crucial. Early treatment helps avoid scar formation.
  • StatPearls: Acitretin [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)ZitoPatrick M.PMUniversity of Miami; Miller School of MedicineMazzoniThomasTBOOK
  • Acitretin belongs to a group of drugs known as retinoids. Retinoids include natural and synthetic compounds that have similar activity to vitamin A. Vitamin A helps regulate the immune system, impacts cellular growth, differentiation, proliferation, and plays a role in embryonic development. Other effects of retinoids include immunologic anti-inflammatory effects, induction of apoptosis, and inhi…
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