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18,880 results
  • Varicella Pneumonia in an Immunocompetent Middle-aged Adult Male: A Case Report. [Journal Article]
    JNMA J Nepal Med Assoc. 2022 Jul 01; 60(251):651-653.Shrestha N, Bhatta K, … Khatun S
  • Varicella pneumonia is uncommon among adults and can present as potentially life-threatening complications of varicella. Here we report a case of a 43-year-old man with no known history of chronic disease and no allergic history who presented to our hospital emergency department with widespread skin eruptions over the entire body and hemoptysis. Varicella pneumonia was diagnosed based on the pati…
  • Empirical intravenous aciclovir therapy in a suspected case of acute encephalitis. [Journal Article]
    Trop Doct. 2023 Jan 24 [Online ahead of print]Divyashree K, Singh H, … Bhalla A
  • Herpes simplex encephalitis is the most common cause of sporadic viral encephalitis worldwide but presents as a diagnostic challenge at many settings due to its non-specific symptoms, which can be easily mistaken for systemic infection or metabolic encephalopathy. It has diverse range of presentations from fever, altered sensorium, nausea, vomiting, meningismus to seizures, neurological deficits …
  • Acute kidney injury in bortezomib-treated patients with multiple myeloma. [Journal Article]
    Nephrol Dial Transplant. 2023 Jan 20 [Online ahead of print]Song SM, Jeon J, … Lee JE
  • CONCLUSIONS: Development of AKI was often observed in the absence of TLS in patients with MM after treatment with bortezomib. In addition, the risk factors of AKI and TLS varied widely. These findings indicate the potential nephrotoxicity of bortezomib irrespective of TLS in patients with decreased kidney function.
  • Herpes Zoster Following COVID-19 Vaccine Booster. [Case Reports]
    Am J Case Rep. 2023 Jan 18; 24:e938667.Shahrudin MS, Mohamed-Yassin MS, Nik Mohd Nasir NM
  • BACKGROUND Herpes zoster is a condition in which there is reactivation of varicella zoster virus (VZV), which is usually seen in the elderly and those with immunocompromised states. Recently, however, there have been many reports of herpes zoster after administration of COVID-19 vaccines, although initial trials showed that these vaccines have good safety and immunogenicity profiles. At the time …
  • [Chinese expert consensus on diagnosis and treatment of viral corneal endotheliitis (2023)]. [Journal Article]
    Zhonghua Yan Ke Za Zhi. 2023 Jan 11; 59(1):13-19.Ocular Infection Group of Chinese Ophthalmologist Association
  • Viral corneal endotheliitis, a blinding corneal disease, is often misdiagnosed due to the diverse clinical manifestations, complex conditions, unclear diagnostic criteria, and limited methods of ocular virus detection. In addition, there is still a lack of unified and standardized treatment for viral corneal endotheliitis. The consensus, basing upon the latest research progress and expert recomme…
  • Aciclovir-induced neurotoxicity. [Journal Article]
    Pract Neurol. 2022 Dec 08 [Online ahead of print]Vonberg FW, Dawson A, … Davies N
  • Aciclovir-induced neurotoxicity results from the accumulation of aciclovir and its metabolite 9-carboxymethoxymethylguanine (CMMG). It occurs predominantly in older patients with impaired renal function and is characterised by a combination of confusion and psychiatric changes. Seizures, myoclonus and dysarthria may also occur. Critically, peritoneal dialysis has little effect on reversing the to…
  • Cytotoxic corpus callosum lesion and mild CSF pleocytosis during hantavirus infection: a case report. [Case Reports]
    Ther Adv Neurol Disord. 2022; 15:17562864221144808.Straeten FA, Meyer Zu Hörste G
  • A middle-aged, previously healthy male patient presented with high fever, headache, and aching limbs for 3 days. Laboratory results showed signs of acute kidney injury, elevated procalcitonin, and mild thrombocytopenia. On neurological examination, he had no focal neurological deficits, especially no meningism or visual disturbances. Cerebrospinal fluid (CSF) examination showed mild lymphocytic p…
  • Herpes Simplex Virus Encephalitis: An Unexpected Outcome in a Polytrauma Patient. [Case Reports]
    J Coll Physicians Surg Pak. 2022 Dec; 32(12):SS160-SS161.Sarwar M, Niazi SK, … Imtiaz A
  • An 84-year male was brought in the emergency after a road traffic accident leading to polytrauma with deteriorating consciousness. Prolonged unexplained unconsciousness led to cerebrospinal fluid examination. The polymerase chain reaction (PCR) of cerebrospinal fluid (CSF) was found to be positive for HSV-1 DNA. The patient was started on intravenous acyclovir and the consciousness level of the p…
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