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495 results
  • Will the polyphenol and adapalene combination be a good strategy on acne vulgaris? [Journal Article]
    Med Hypotheses 2019; 133:109409Janani SK, Sureshkumar R, … Vasanthi C
  • Acne vulgaris is a common disease which affects about 85% of the population. Various topical drugs are available, but the retinoid derivatives are mostly taken into consideration. They are used as a first-line treatment drugs. However, they also have few side effects. Whereas, adapalene which is a third generation topical retinoid has fewer side effects compared to other derivatives. In this, we …
  • Carboxylation of Aryl Triflates with CO2 Merging Palladium and Visible-Light-Photoredox Catalysts. [Journal Article]
    Org Lett 2019; 21(12):4632-4637Bhunia SK, Das P, … Jana R
  • We report herein a visible-light-promoted, highly practical carboxylation of readily accessible aryl triflates at ambient temperature and a balloon pressure of CO2 by the combined use of palladium and photoredox Ir(III) catalysts. Strikingly, the stoichiometric metallic reductant is replaced by a nonmetallic amine reductant providing an environmentally benign carboxylation process. In addition, o…
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