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(adefovir dipivoxil)
1,076 results
  • Adefovir dipivoxil inhibits APL progression through degradation of the oncoprotein PML-RARA. [Letter]
    Exp Hematol Oncol. 2022 Nov 20; 11(1):103.Gong X, Kong P, … Liu W
  • Acute promyelocytic leukemia (APL) is highly aggressive and is frequently associated with disseminated intravascular coagulation and high early death rates. Although all-trans retinoic acid (RA) induces complete remission in a high proportion of patients with APL, there are limited treatments for APL patients with RA resistance. Here we report an atypical APL patient, with an APL-like disease tha…
  • Drug-induced Fanconi syndrome in patients with kidney allograft transplantation. [Journal Article]
    Front Immunol. 2022; 13:979983.Tang Z, Li T, … Peng L
  • CONCLUSIONS: For the first time, drug-induced Fanconi syndrome after kidney transplantation was reported. These results confirmed that the long-term use of ADV or tacrolimus after kidney transplantation may have serious consequences, some of which are irreversible. Greater understanding of Fanconi syndrome after kidney transplantation is necessary in order to avoid incorrect and missed diagnosis.
  • Tenofovir Alafenamide Rescues Renal Tubules in Patients with Chronic Hepatitis B. [Journal Article]
    Life (Basel). 2021 Mar 23; 11(3)Sano T, Kawaguchi T, … Torimura T
  • Nucles(t)ide analogs (NAs) are effective for chronic hepatitis B (CHB). NAs suppress hepatic decompensation and hepatocarcinogenesis, leading to a dramatic improvement of the natural course of patients with CHB. However, renal dysfunction is becoming an important issue for the management of CHB. Renal dysfunction develops in patients with the long-term treatment of NAs including adefovir dipivoxi…
  • Fanconi syndrome induced by adefovir dipivoxil: a case report and clinical review. [Case Reports]
    J Int Med Res. 2020 Oct; 48(10):300060520954713.Song K, Yan Q, … Gao H
  • More than 150 cases of Fanconi syndrome (FS) or hypophosphatemia osteomalacia induced by low-dose adefovir dipivoxil (ADV) have been reported since 2002, when ADV was introduced for the long-term treatment of hepatitis B virus (HBV) infection. Because the life expectancy of HBV-infected individuals has increased, the adverse effects of long-term treatment with antiviral therapies are increasingly…
  • Ten-year follow-up of a randomized controlled clinical trial in chronic hepatitis delta. [Randomized Controlled Trial]
    J Viral Hepat. 2020 12; 27(12):1359-1368.Wranke A, Hardtke S, … Yurdaydin C
  • Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis. PEG-interferon alpha-2a (PEG-IFNα-2a) is the only effective treatment but its long-term clinical impact is unclear. The aim of this study was to investigate the long-term outcome after 48 weeks of pegylated interferon alpha-2a therapy. We performed a retrospective follow-up study of the Hep-Net-International-Del…
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