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283,450 results
  • PDQ Cancer Information Summaries: Childhood Adrenocortical Carcinoma Treatment (PDQ®): Patient Version [BOOK]
    . National Cancer Institute (US): Bethesda (MD) PDQ Pediatric Treatment Editorial Board BOOK
  • This PDQ cancer information summary has current information about the treatment of childhood adrenocortical carcinoma. It is meant to inform and help patients, families, and caregivers. It does not give formal guidelines or recommendations for making decisions about health care. Editorial Boards write the PDQ cancer information summaries and keep them up to date. These Boards are made up of exper…
  • Type 2 Autoimmune Polyglandular Syndrome Presenting with Hyperpigmentation and Amenorrhea. [Case Reports]
    Cureus. 2020 Apr 21; 12(4):e7772.Gaba N, Gaba S, … Gupta M
  • A 36-year-old female presented with lethargy, anorexia, nausea, hyperpigmentation, weight loss and amenorrhea for six months. On examination, she had hyperpigmentation of face, hands and oral mucosa. Investigations revealed adrenal insufficiency and subclinical hyperthyroidism with elevated anti-thyroid peroxidase antibodies. Adrenal insufficiency in combination with Grave's disease and/or type 1…
  • Chemerin as a driver of hypertension: a consideration. [Journal Article]
    Am J Hypertens. 2020 May 26 [Online ahead of print]Ferland DJ, Mullick AE, Watts SW
  • The protein chemerin (tazarotene induced gene, TIG2; RARRES2) is a relatively new adipokine. Many studies support that circulating chemerin levels associate strongly and positively with BMI, visceral fat and blood pressure. Here, we focus on the specific relationship of chemerin and blood pressure with the goal of understanding whether and how chemerin drives (pathological) changes in blood press…
  • 18F-FDG PET/CT Imaging of Adrenal Liposarcoma. [Journal Article]
    Clin Nucl Med. 2020 May 20 [Online ahead of print]Wang R, Fan Q, Tian R
  • Liposarcoma is a common soft tissue sarcoma in retroperitoneum, but adrenal liposarcoma is rare. We here described a 61-year-old man with left-upper-quadrant pain, hypertension, and weight loss. Abdominal CT showed a large, heterogeneously enhanced mass on the left adrenal area, which compressed the surrounding pancreas, spleen, and left kidney. Subsequent FDG PET/CT demonstrated heterogeneous up…
  • CT and MR imaging of acute adrenal disorders. [Review]
    Abdom Radiol (NY). 2020 May 26 [Online ahead of print]Udare A, Agarwal M, … Schieda N
  • The adrenal glands may be overlooked when evaluating acutely ill patients. Acute adrenal disorders may result from complications of an underlying systemic disease, which may be unsuspected clinically. Various acute adrenal emergencies including trauma, spontaneous hemorrhage, infarction and infection can be diagnosed using CT and MRI; however, in uncertain cases follow-up to resolution of imaging…
  • Effect of Stress on Neuroimmune Processes. [Review]
    Clin Ther. 2020 May 22 [Online ahead of print]Theoharides TC
  • CONCLUSIONS: Understanding and addressing the connection between stress and MCs is important in clarifying the pathogenesis and developing effective treatments for diseases that worsen with stress and involve inflammation, such as AD and ASD.
  • The intersections of stress, anxiety and epilepsy. [Journal Article]
    Int Rev Neurobiol. 2020; 152:195-219.Salpekar JA, Basu T, … Maguire J
  • Stress is ubiquitous in chronic medical conditions; however, the connections to psychiatric and neurologic conditions are not always clearly established. Epilepsy is a unique illness that is intimately intertwined with stress and anxiety not only as a result of the disease process but also as a cause of disease exacerbation. Anxiety and depression also involve stress management and often overlap …
  • Stress and cortisol in Parkinson's disease. [Journal Article]
    Int Rev Neurobiol. 2020; 152:131-156.van Wamelen DJ, Wan YM, … Jenner P
  • Stress is ubiquitous with many factors contributing to its effects, including psychological responses and associated biological factors, including cortisol related physiological responses, and inflammation. Also in Parkinson's disease there is growing evidence for the role of stress in some key symptoms, even stretching to the prodromal stage. Here we discuss the possible contributions of the ran…
  • Stress, cortisol and suicide risk. [Journal Article]
    Int Rev Neurobiol. 2020; 152:101-130.O'Connor DB, Gartland N, O'Connor RC
  • Suicide is a global health issue accounting for at least 800,000 deaths per annum. Numerous models have been proposed that differ in their emphasis on the role of psychological, social, psychiatric and neurobiological factors in explaining suicide risk. Central to many models is a stress-diathesis component which states that suicidal behavior is the result of an interaction between acutely stress…
  • The Peacock study: feasibility of the dynamic characterisation of the paediatric hypothalamic-pituitary-adrenal function during and after cardiac surgery. [Journal Article]
    BMC Cardiovasc Disord. 2020 May 25; 20(1):245.Fudulu DP, Angelini GD, … Gibbison B
  • CONCLUSIONS: We report for the first time, the use of an automated microdialysis sampling system to evaluate the paediatric adrenal response in children. Changes in cortisol and cortisone could be measured, and the concentration of cortisol in the tissues increased after the end of cardiac surgery. The method has wide application to measure other hormones dynamically and frequently without the limitation of the circulating blood volume. The data from the main study will clarify how these cortisol profiles vary with age, pathology, type of procedure and correlation to clinical outcomes.
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