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21,368 results
  • StatPearls: Cancer, Adrenal [BOOK]
    StatPearls Publishing: Treasure Island (FL) Torti Jeronimo F. JF Universidad Nacional de Cuyo Correa Ricardo R University of Arizona BOOK
  • The adrenal is an endocrine organ which has two physiological functions. The outer adrenal cortex produces steroid hormones, including glucocorticoids such as cortisol, and mineralocorticoids (aldosterone, and the androgen dehydroepiandrosterone. The glucocorticoids play a role in carbohydrate, protein, and fat metabolism. The mineralocorticoids are essential for the sodium (Na) and potassium (K)…
  • [Update on Li-Fraumeni syndrome]. [Review]
    Pathologe 2019Dutzmann CM, Vogel J, … Dörgeloh BB
  • The Li-Fraumeni syndrome (LFS, online Mendelian inheritance in man, OMIM #151623) is considered to be one of the currently known most aggressive cancer predisposition syndromes. The heterogeneous spectrum of tumors is dominated by bone and soft tissue sarcomas, various brain tumors, premenopausal breast cancer and adrenocortical carcinoma (ACC). Even in childhood the cancer risk is very strongly …
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