- Trichostrongylus and Haemonchus anthelmintic resistance in naturally infected sheep from southern Brazil. [Journal Article]
- AAAn Acad Bras Cienc 2014; 86(2):777-784
- The anthelmintic resistance in small ruminants is a common problem and concern worldwide. The aim of this study was to verify anthelmintic treatment efficacy in naturally infected sheep. This study w...
The anthelmintic resistance in small ruminants is a common problem and concern worldwide. The aim of this study was to verify anthelmintic treatment efficacy in naturally infected sheep. This study was conducted on nine herds that used the same anthelmintic management for over a year. In each farm, the animals were divided into two groups: untreated control group (n = 5) and treated (n = 10) according to the number of eggs per gram of feces (EPG). The treatment effect was checked based on EPG results and larval culture performed before treatment and 10 days after treatment. Significant differences were not observed (P > 0.05) on EPG results between untreated and treated groups. The coproculture showed that the animals were infected primarily by Haemonchus spp., Trichostrongylus spp., Teladorsagia spp., Cooperia spp. and Oesophagostomum spp. In all farms, anthelmintic resistance by genera Haemonchus and Trichostrongylus was found, but this resistance varied greatly between farms. Haemonchus spp. showed resistance to closantel, levamisole, and albendazole. Trichostrongylus spp. was shown to be resistant to closantel, levamisole, and albendazole. The drugs tested showed to be efficient against the genera Teladorsagia, Cooperia, and Oesophagostomum. Based on these results, we conclude that the anthelmintic resistance to the tested drugs is a problem present in the farms evaluated.
- Subcutaneous nodules of cysticercosis as a sign of asymptomatic neurocysticercosis in an HIV positive patient. [Case Reports]
- RSRev Soc Bras Med Trop 2018 Nov-Dec; 51(6):861-863
- Cysticercosis is caused by the hematogenous dissemination of the larval form (cysticercus) of Taenia solium. It can affect any organ or tissue in the body but commonly affects the subcutaneous tissue...
Cysticercosis is caused by the hematogenous dissemination of the larval form (cysticercus) of Taenia solium. It can affect any organ or tissue in the body but commonly affects the subcutaneous tissue, central nervous system, eyes, and skeletal muscle. Skin lesions can assist as a marker in the diagnosis of asymptomatic neurocysticercosis in endemic areas. A 49-year-old HIV positive man presented with multiple cutaneous nodules confirmed as cysticercomas which led to the diagnosis of asymptomatic neurocysticercosis. He was successfully treated with albendazole and steroids at recommended doses with no adverse effects.
- Utilization of Antenatal Care Services in Dalit Communities in Gorkha, Nepal: A Cross-Sectional Study. [Journal Article]
- JPJ Pregnancy 2018; 2018:3467308
- CONCLUSIONS: Even though there is reasonable good utilization rate of antenatal service, the study revealed that low education and awareness among mothers, low socioeconomic condition, early marriage and pregnancy, inappropriate antenatal health check-up, and cultural taboos were significant factors affecting the satisfactory utilization of services among the Dalit community. Hence, there is a need to emphasize on raising awareness of Dalit mothers for receiving available prenatal services.
- Cystic echinococcosis in the thigh: a case report. [Journal Article]
- IInfection 2018 Dec 03
- Intramuscular cystic echinococcosis is a very rare occurrence. Herein we report a case of a 37-year-old patient who presented with progressive swelling of his left thigh. Ultrasound evaluation showed...
Intramuscular cystic echinococcosis is a very rare occurrence. Herein we report a case of a 37-year-old patient who presented with progressive swelling of his left thigh. Ultrasound evaluation showed a multicystic, encapsulated lesion (16 × 3.5 × 8.5 cm) in the M. vastus lateralis, and serology confirmed the diagnosis of Echinococcus granulosus s.l. infection. No additional cysts were detected upon total body CT scan. The patient was treated with albendazole pre-operatively; surgical resection of the mass was then successfully performed. The patient feels well and no signs of residual infestation were seen after 2 years of follow-up.
- Efficacy and safety of ascending dosages of tribendimidine against hookworm infections in children: a randomized controlled trial. [Journal Article]
- CIClin Infect Dis 2018 Nov 29
- CONCLUSIONS: A 400 mg dose of tribendimidine yielded the highest efficacy and was well tolerated. Since children were mostly lightly infected, further investigations with tribendimidine against moderate/heavy hookworm infection are needed.
- Right ventricular hydatid cyst presented as tachyarrhythmia. [Journal Article]
- ACAsian Cardiovasc Thorac Ann 2018 Nov 28; :218492318817665
- Cardiac hydatidosis is a rare presentation of echinococcus granulosus infestation. We report the case of 57-year-old man who presented with syncope due to ventricular tachycardia and was managed with...
Cardiac hydatidosis is a rare presentation of echinococcus granulosus infestation. We report the case of 57-year-old man who presented with syncope due to ventricular tachycardia and was managed with antiarrhythmic drugs for an acute episode. Echocardiography and cardiac magnetic resonance imaging suggested a 1 cm right ventricular hydatid cyst. In view of the control of arrhythmia on antiarrhythmic drugs and the small size of the cyst, the patient was treated with albendazole 400 mg twice a day for 4 weeks. He was asymptomatic with normal liver function during follow-up, and repeat echocardiography after 1 year revealed disappearance of the intramyocardial lesion.
- [Prevalence of Malaria, Intestinal and Urinary parasite infections in Kalifabougou, Mali]. [Journal Article]
- MMMali Med 2018; 33(1):10-15
- CONCLUSIONS: Praziquantel and Albendazole-based MDA and Artemisinin based combined therapy (ACTs) could explain theobserved low prevalence of helminthiasis and malaria in Kalifabougou, Mali.
- Ovarian Cancer or Hydatidosis? A Case Report. [Journal Article]
- IJIran J Parasitol 2018 Jul-Sep; 13(3):500-504
- Echinococcus granulosus has been described as the common etiology of hydatid cysts in many parts of the world. A 54-yr-old female with lower abdominal pain referred to Gynecology Ward of Sari Imam Kh...
Echinococcus granulosus has been described as the common etiology of hydatid cysts in many parts of the world. A 54-yr-old female with lower abdominal pain referred to Gynecology Ward of Sari Imam Khomeini Hospital, Iran in 2016. Sonography was carried out and cysts in ovaries and liver were observed. The cysts of liver seemed to be hydatidosis but physicians were suspected about ovarian cystic mass. Anti-Echinococcus antibodies (ELISA) screen was positive. The operation was done on her and treatment by albendazole started one week before surgery and continued after discharge from the hospital. Pathology confirmed hydatidosis in ovary, also patient follow-up was performed for three months by abdominal CT scan that showed peritoan full of many small hydatid cysts. Uncommon locations for constitution of hydatid cysts such as ovary and peritoan often make the diagnosis very difficult. Hydatidosis is considered in differential diagnosis of any cysts of the entire body, especially in endemic countries such as Iran.
- Optic Nerve Cysticercosis at the Orbital Apex Presenting as Optic Neuritis. [Journal Article]
- JOJ Ophthalmic Vis Res 2018 Oct-Dec; 13(4):508-510
- CONCLUSIONS: A high index of clinical suspicion along with appropriate imaging methods can help diagnose rare presentations of ocular cysticercosis. With timely management, successful outcomes can be obtained.
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- Factors Associated With Cysticidal Treatment Response in Extraparenchymal Neurocysticercosis. [Journal Article]
- JCJ Clin Pharmacol 2018 Nov 26
- Extraparenchymal neurocysticercosis is the most severe form of cysticercosis, and response to treatment is suboptimal. We sought to determine how demographic and clinical characteristics and albendaz...
Extraparenchymal neurocysticercosis is the most severe form of cysticercosis, and response to treatment is suboptimal. We sought to determine how demographic and clinical characteristics and albendazole sulfoxide concentrations were related to cysticidal treatment response. We conducted a longitudinal study of 31 participants with extraparenchymal vesicular parasites who received the same treatment, albendazole 30 mg/kg/day for 10 days with dexamethasone 0.4 mg/kg/day for 13 days, followed by a prednisone taper. Response to treatment was determined by parasite volumes before and 6 months after treatment. Eight participants (25.8%) had a complete treatment response, 16 (51.6%) had a treatment response > 50% but < 100%, and 7 (22.6%) had a treatment response < 50%. Complete treatment response was significantly associated with higher concentrations of albendazole sulfoxide (P = .032), younger age (P = .032), fewer cysts (P = .049) and lower pretreatment parasite volume (P = .037). Higher number of previous cysticidal treatment courses was associated with a noncomplete treatment response (P = .023). Although the large proportion of participants with less than a complete response emphasizes the need to develop more efficacious pharmacologic regimens, the association of albendazole sulfoxide concentrations with treatment response highlights the importance of optimizing existing therapeutic regimens. In addition, the association of treatment response with parasite volume emphasizes the importance of early diagnosis.