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(albendazole )
5,657 results
  • Albendazole solution formulation via vesicle-to-micelle transition of phospholipid-surfactant aggregates. [Journal Article]
  • DDDrug Dev Ind Pharm 2018 Feb 20; :1-9
  • Vinarov Z, Gancheva G, … Tcholakova SS
  • CONCLUSIONS: (1) A new drug delivery system for parenteral delivery of albendazole is proposed, offering high drug solubility and low toxicity of the materials used; (2) New insights on the role of surface curvature on albendazole solubilization in surfactant and surfactant-phospholipid aggregates are provided.A new albendazole delivery system with high drug load and low toxicity of the materials used was developed. The high solubility of albendazole was explained with vesicle-to-micelle transition due to the larger interfacial curvature preferred for albendazole solubilization locus.
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