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10,159 results
  • Disturbances of purinergic system in affective disorders and schizophrenia. [Review]
    Psychiatr Pol 2019; 53(3):577-587Malewska-Kasprzak MK, Permoda-Osip A, Rybakowski J
  • Purinergic system plays a role in the regulation of many psychological processes, including mood and activity. It consists of P1 receptors, with adenosine as the agonist, and P2 receptors, activated by nucleotides (e.g., adenosine 5'-triphosphate - ATP). Propounded disturbances of uric acid in affective disorders were related to the introduction of lithium for the treatment of these disorders in …
  • Drug-drug interactions when treating HIV-related metabolic disorders. [Journal Article]
    Expert Opin Drug Metab Toxicol 2019Gutierrez MDM, Mateo MG, … Domingo P
  • Introduction: Drug-drug interactions (DDI) between antiretroviral drugs and drugs for the treatment of metabolic disturbances in people living with human immunodeficiency virus (HIV) (PLWH) have represented a problem of paramount importance in the recent times. The problem has been mainly driven by sharing common metabolizing pathways. This problem has classically been worsened by the frequent us…
  • Effects of Alismatis Rhizoma and Rhizoma Smilacis Glabrae Decoction on Hyperuricemia in Rats. [Journal Article]
    Evid Based Complement Alternat Med 2019; 2019:4541609Cheng S, Sun H, … Chen J
  • The combination of Alismatis Rhizoma (AR) and Rhizoma Smilacis Glabrae (RSG), as Chinese herb medicine, has been used for their uric acid-lowering effect. However, the effects and mechanism of the combination of the two medicines have not been fully reported. Therefore, to explore the effects of AR-RSG combination decoction on the treatment of chronic hyperuricemia (HUA) in rats as well as the un…
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