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(alosetron)
341 results
  • Anti-inflammatory effects of alosetron mediated through 5-HT3 receptors on experimental colitis. [Journal Article]
    Res Pharm Sci 2019; 14(3):228-236Motavallian A, Minaiyan M, … Andalib S
  • Development of new medicine with fewer deleterious effects and more efficacies for treatment of inflammatory bowel disease is needed. 5-Hydroxytryptamine 3 receptor (5-HT3R) antagonists have exhibited analgesic and anti-inflammatory features in vitro and in vivo. The present study was designed to evaluate the anti-inflammatory effect of alosetron, a 5-HT3R antagonist, on trinitrobenzenesulfonic a…
  • Update on Pharmacotherapy for Irritable Bowel Syndrome. [Review]
    Curr Gastroenterol Rep 2019; 21(6):25Munjal A, Dedania B, Cash B
  • Irritable bowel syndrome (IBS) is a functional GI disorder that affects a large percentage of the population and presents a significant socio-economic burden on the society. In this article, we reviewed the evidence supporting various pharmacological treatment options for IBS.
  • Drugs and Lactation Database (LactMed): Alosetron [BOOK]
    National Library of Medicine (US): Bethesda (MD)BOOK
  • No information is available on the use of alosetron during breastfeeding. Because of relatively high protein binding and only moderate bioavailability, exposure of the breastfed infant is likely to be low. Until more data are available, alosetron should only be used with careful infant monitoring during breastfeeding.
  • Acupuncture for Diarrhoea-Predominant Irritable Bowel Syndrome: A Network Meta-Analysis. [Review]
    Evid Based Complement Alternat Med 2018; 2018:2890465Zhu L, Ma Y, … Shu Z
  • CONCLUSIONS: Acupuncture may improve diarrhoea-predominant irritable bowel syndrome better than drugs and has the fewest side effects. Sham acupuncture may have curative effect except for placebo effect. In the future, it is necessary to perform highly qualified research to prove this result. Pinaverium bromide also has good curative effects with fewer side effects than other drugs.
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