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(alpha1 antitrypsin)
2,936 results
  • Role for Cela1 in Postnatal Lung Remodeling and AAT-deficient Emphysema. [Journal Article]
  • AJAm J Respir Cell Mol Biol 2018 Feb 08
  • Joshi R, Heinz A, … Varisco BM
  • CONCLUSIONS: Cela1 is important in physiologic and pathologic stretch-dependent remodeling processes in the postnatal lung. AAT is an important regulator of this process. Our findings provide proof-of-concept for the development of anti-Cela1 therapies to prevent and/or treat AAT-deficient emphysema.
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