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(alpha1 proteinase inhibitor human)
12,236 results
  • Bone Density in Children with Chronic Liver Disease Correlates with Growth and Cholestasis. [Journal Article]
  • HepHepatology 2018 Jul 31
  • Loomes KM, Spino C, … Childhood Liver Disease Research Network (ChiLDReN)
  • CONCLUSIONS: CIC patients had significant bone deficits that persisted after adjustment for height and weight and generally did not correlate with degree of cholestasis. In ALGS, low BMD and BMC reference Z-scores were explained by poor growth. Anthropometrically-adjusted DXA measures in ALGS correlate with markers of cholestasis and fx history. Reduced bone density in this population is multifactorial and related to growth, degree of cholestasis, fracture vulnerability, and contribution of underlying genetic etiology. This article is protected by copyright. All rights reserved.
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