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6,092 results
  • Extraction Socket Preservation Using Growth Factors and Stem Cells: a Systematic Review. [Review]
    J Oral Maxillofac Res 2019 Jul-Sep; 10(3):e7Pranskunas M, Galindo-Moreno P, Padial-Molina M
  • CONCLUSIONS: In general, the use of mesenchymal stem cells or bioactive osteogenic molecules favours bone regeneration after tooth extraction, as evaluated clinically, radiographically and histologically. However, specific differences that support particular recommendations are still unclear in light of the current published evidence. Future studies should include the standardization of the mesenchymal stem cells selection and purification as well as dosage and delivery methods of bioactive molecules.
  • Molecular and Cellular Aspects of Socket Healing in the Absence and Presence of Graft Materials and Autologous Platelet Concentrates: a Focused Review. [Review]
    J Oral Maxillofac Res 2019 Jul-Sep; 10(3):e2de Sousa Gomes P, Daugela P, … Fernandes MH
  • CONCLUSIONS: Tooth extraction initiates a convoluted set of orderly biological events in the alveolus, aiming wound closure and socket healing. The healing process comprises a wide range of events, regulated by the interplay of cytokines, chemokines and growth factors that determine cellular recruitment, proliferation and differentiation in the healing milieu, in a space- and time-dependent choreographic interplay. Additionally, the healing process may further be modulated by the implantation of grafting materials or autologous platelet concentrates within the tooth socket, aiming to enhance the regenerative outcome.
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