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471,831 results
  • "In-loop" carbonylation - a simplified method for carbon-11 labeling of drugs and radioligands. [Journal Article]
    J Labelled Comp Radiopharm 2019Ferrat M, Dahl K, … Schou M
  • Transition-metal mediated carbonylation with 11 C-labelled carbon monoxide ([11 C]CO) is a versatile method for introducing 11 C (t1/2 = 20.3 min) into drugs and radioligands for subsequent use in positron emission tomography (PET). The aim of the current study was to perform the 11 C-carbonylation reaction on the interior surface of a stainless-steel loop used for high performance liquid chromat…
  • Effect of Pore Confinement of NaNH2 and KNH2 on Hydrogen Generation from Ammonia. [Journal Article]
    J Phys Chem C Nanomater Interfaces 2019; 123(35):21487-21496Chang F, Wu H, … de Jongh PE
  • The development of efficient catalysts for hydrogen generation via ammonia decomposition is crucial for the use of ammonia as an energy carrier. Here, we report the effect of pore confinement of NaNH2 and KNH2 on ammonia decomposition catalysis. For the first time, Ni- or Ru-doped NaNH2 and KNH2 were confined in carbon nanopores using a combination method of solution impregnation and melt infiltr…
  • The discovery and optimization of a series of 2-aminobenzoxazole derivatives as ChemR23 inhibitors. [Journal Article]
    Bioorg Med Chem 2019; :115091Imaizumi T, Kobayashi A, … Otsubo N
  • A structural class of 2-aminobenzoxazole derivatives possessing biphenyltetrazole was discovered to be potent human ChemR23 inhibitors. We initially tried to improve the potency of compound 1, which was found through in-house screening using the human plasmacytoid dendritic cell (pDC)-like cell line CAL-1. The introduction of a chiral methyl moiety at a benzylic position in a center of compound 1…
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