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(aminocaproic acid)
5,698 results
  • Antifibrinolytic therapy for preventing oral bleeding in people on anticoagulants undergoing minor oral surgery or dental extractions. [Review]
  • CDCochrane Database Syst Rev 2018 07 02; 7:CD012293
  • Engelen ET, Schutgens RE, … van Galen KP
  • CONCLUSIONS: Based on the results of this Cochrane Review, there seems to be a beneficial effect of locally applied TXA in preventing oral bleeding in people on continuous treatment with VKAs undergoing minor oral surgery or dental extractions. However, the small number of identified randomised controlled trials, the relatively small number of participants included in the trials and the differences in standard therapy and treatment regimens between trials, do not allow us to conclude definite efficacy of antifibrinolytic therapy in this population.We were unable to identify any eligible trials in people on continuous treatment with DOACs undergoing oral or dental procedures. Therefore, a beneficial effect of antifibrinolytic therapy can currently only be assumed based on data from the people using VKAs.
  • Red urine, updated for the nephrologist: a case report. [Journal Article]
  • BNBMC Nephrol 2018 Jun 08; 19(1):133
  • Le Joncour A, Mesnard L, … Robert T
  • CONCLUSIONS: Hemoglobin electrophoresis should be performed in cases of gross hematuria. Coupled with other non-invasive evaluation, this could avoid renal biopsy and its associated complications.
  • Antifibrinolytic Agents in Plastic Surgery: Current Practices and Future Directions. [Journal Article]
  • PRPlast Reconstr Surg 2018; 141(6):937e-949e
  • Brown S, Yao A, Taub PJ
  • CONCLUSIONS: Tranexamic acid and ε-aminocaproic acid are widely used to reduce blood loss and transfusion requirements in craniofacial and orthognathic surgery, without an increased risk of adverse events. Intravenous administration is most commonly used, although topical formulations show similar efficacy with a reduced systemic distribution. Tranexamic acid has also emerged as a promising agent in aesthetic surgery and burn care, due to its favorable safety profile and role in reducing blood loss, achieving an improved surgical field, and reducing edema and ecchymosis. Further investigation of these agents in the fields of burn care, aesthetic surgery, and microsurgery is warranted to standardize protocols for clinical use.
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