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(aminolevulinic acid)
9,918 results
  • Optimizing maximum resection of glioblastoma: Raman spectroscopy versus 5-aminolevulinic acid. [Journal Article]
    J Neurosurg. 2022 Dec 23 [Online ahead of print]Herta J, Cho A, … Wolfsberger S
  • CONCLUSIONS: According to the study data, RS is capable of detecting tumor-infiltrated brain with higher sensitivity but lower specificity than the current standard of 5-ALA. With further technological and workflow advancements, RS in combination with protoporphyrin IX fluorescence may contribute to pathology-tailored glioma resection in the future.
  • AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. [Practice Guideline]
    Gastroenterology. 2023 Jan 13 [Online ahead of print]Wang B, Bonkovsky HL, … Balwani M
  • The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase. Acute intermittent porphyria is the most common type of AHP, with an estimated prevalence of patients with symptoms of approximately 1 in 100,000. The maj…
  • Understanding Carbohydrate Metabolism and Insulin Resistance in Acute Intermittent Porphyria. [Review]
    Int J Mol Sci. 2022 Dec 20; 24(1)Solares I, Jericó D, … Fontanellas A
  • Porphobilinogen deaminase (PBGD) haploinsufficiency (acute intermittent porphyria, AIP) is characterized by neurovisceral attacks associated with high production, accumulation and urinary excretion of heme precursors, δ-aminolevulinic acid (ALA) and porphobilinogen (PBG). The estimated clinical penetrance for AIP is extremely low (<1%), therefore it is likely that other factors may play an import…
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