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5,396 results
  • Drugs and Lactation Database (LactMed) [BOOK]
  • BOOKNational Library of Medicine (US): Bethesda (MD)
  • An expert panel considers use of aminophylline to be acceptable during breastfeeding.[1] Maternal aminophylline use may occasionally cause stimulation and irritability and fretful sleep in infants. N...
  • No Requirement for Targeted Theophylline Levels for Diuretic Effect of Aminophylline in Critically Ill Children. [Journal Article]
  • PCPediatr Crit Care Med 2018; 19(8):e425-e432
  • Park K, Trout LC, … Halstead ES
  • CONCLUSIONS: Aminophylline administration provided a measure of increased diuresis, regardless of dosage, and theophylline trough levels. Therefore, achieving a prescribed therapeutic trough level may not be necessary for full diuretic effect. Because, as opposed to the diuretic effect, the side effect profile of aminophylline is dose-dependent, low maintenance dosing may optimize the balance between providing adjunctive diuretic effect while minimizing the risk of toxicity.
  • What do Cochrane systematic reviews say about cardiac arrest management? [Review]
  • SPSao Paulo Med J 2018; 136(2):170-176
  • Pacheco RL, Trevizo J, … Riera R
  • CONCLUSIONS: This review included nine Cochrane systematic reviews that provided a diverse range of qualities of evidence (unknown to high) regarding interventions that are used in management of cardiac arrest. High-quality evidence was found by two systematic reviews as follows: (a) increased survival until hospital discharge with continuous compression, compared with interrupted chest compression, both administered by an untrained person and (b) no difference regarding the return of spontaneous circulation, comparing aminophylline and placebo, for bradyasystolic patients under cardiac arrest. Further studies are needed in order to reach solid conclusions.
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