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9,830 results
  • Tools to compare antibody gold nanoparticle conjugates for a small molecule immunoassay. [Journal Article]
    Mikrochim Acta. 2023 Jan 20; 190(2):62.Conrad M, Proll G, … Gauglitz G
  • Antibody gold nanoparticle conjugates as recognition elements are essential for the overall performance of lateral flow assays. When immobilizing antibodies on gold nanoparticles, the challenge is to prevent aggregation and to ensure that the antibodies are correctly oriented so that they remain functional and their paratopes remain accessible. There are many methods available, and it is difficul…
  • Amitriptyline intoxication in bullfrogs causes widening of QRS complexes in electrocardiogram. [Journal Article]
    J Vet Med Sci. 2022 Dec 29 [Online ahead of print]Nagano A, Muto M, … Kazama I
  • Amitriptyline intoxication is caused by its suicidal or accidental overdose. In the present study, by intravenously injecting 1.5 or 3.0 mg/kg amitriptyline into bullfrogs, we actually revealed that amitriptyline causes the widening of QRS complexes in electrocardiogram (ECG). In simultaneous recordings of the cardiac action potential, amitriptyline decreased the slope of phase 0 in the action po…
  • Evaluation and Treatment of Vulvodynia: State of the Science. [Review]
    J Midwifery Womens Health. 2022 Dec 19 [Online ahead of print]Schlaeger JM, Glayzer JE, … McFarlin BL
  • Vulvodynia affects 7% of American women, yet clinicians often lack awareness of its presentation. It is underdiagnosed and often misdiagnosed as vaginitis. The etiology of vulvodynia remains unknown, making it difficult to identify or develop effective treatment methods. The purpose of this article is to (1) review the presentation and evaluation of vulvodynia, (2) review the research on vulvodyn…
  • Prescribing for common complications of spinal cord injury. [Journal Article]
    Can Fam Physician. 2022 12; 68(12):885-888.McColl MA, Gupta S, … Smith K
  • CONCLUSIONS: To provide optimal treatment to patients with SCI, family doctors are encouraged to engage in open communication with them about prescription medications, including aspects of cost, polypharmacy, and therapeutic substitutions. Family physicians should also explore interprofessional collaboration with SCI specialists and allied health providers to provide patients with nonpharmacologic strategies tailored to their activity levels and nutritional needs. The Actionable Nuggets mobile app provides family doctors with brief, actionable, evidence-based information on the top 20 health concerns associated with SCI.
  • Efficacy and Safety of Melatonin as Prophylaxis for Migraine in Adults: A Meta-analysis. [Meta-Analysis]
    J Oral Facial Pain Headache. 2022 Summer; 36(3-4):207–219.Puliappadamb HM, Maiti R, … Mishra BR
  • CONCLUSIONS: Melatonin showed a beneficial prophylactic role in migraine, with a better responder rate in comparison to placebo in reducing migraine severity, mean attack duration, mean attack frequency, and analgesic use, but did not show significant effects in comparison to amitriptyline or valproate.
  • Trigeminal trophic syndrome in a pediatric patient with diffuse intrinsic pontine glioma. [Case Reports]
    Pediatr Dermatol. 2022 Nov 21 [Online ahead of print]Hoover E, Jay R, Witman P
  • A 13-year-old girl with a history of diffuse intrinsic pontine glioma (DIPG) suffered from progressively worsening facial ulcerations secondary to paresthesia-induced self-excoriation. She was diagnosed with trigeminal trophic syndrome (TTS) induced by DIPG and struggled to heal her lesions in the background of this excoriation disorder. A multidisciplinary approach that included mood disorder ma…
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