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8,910 results
  • Antidepressants for insomnia in adults. [Review]
  • CDCochrane Database Syst Rev 2018 May 14; 5:CD010753
  • Everitt H, Baldwin DS, … Wilson S
  • CONCLUSIONS: We identified relatively few, mostly small studies with short-term follow-up and design limitations. The effects of SSRIs compared with placebo are uncertain with too few studies to draw clear conclusions. There may be a small improvement in sleep quality with short-term use of low-dose doxepin and trazodone compared with placebo. The tolerability and safety of antidepressants for insomnia is uncertain due to limited reporting of adverse events. There was no evidence for amitriptyline (despite common use in clinical practice) or for long-term antidepressant use for insomnia. High-quality trials of antidepressants for insomnia are needed.
  • Alpha lipoic acid in obstetrics and gynecology. [Journal Article]
  • GEGynecol Endocrinol 2018 May 04; :1-5
  • Di Tucci C, Di Feliciantonio M, … Benedetti Panici P
  • Alpha-Lipoic acid (ALA) is a natural antioxidant synthetized by plants and animals, identified as a catalytic agent for oxidative decarboxylation of pyruvate and α-ketoglutarate. In this review, we a...
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