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7 results
  • [Primary distal renal tubular acidosis in children in the South of Tunisia: study of 15 cases]. [Journal Article]
    Tunis Med 2013; 91(4):258-62Kamoun T, Sfaihi L, … Hachicha M
  • CONCLUSIONS: The distal renal tubular acidosis is a rare pathology in our country but probably under diagnosed. The clinical gravity of this disease and the risk of evolution towards the terminal renal insufficiency justify an antenatal diagnosis to establish a neonatal management or propose a therapeutic interruption of the pregnancy if the distal RTA is associated with a severe pathology.
  • Renal recovery from metabolic acidosis in the rat: no role for glutamine synthetase. [Journal Article]
    Ren Physiol 1984; 7(1):32-45Duong N, Vinay P, … Gougoux A
  • The role of renal glutamine synthesis for the rapid decrease in renal ammoniagenesis occurring early in the recovery phase (24 h) of metabolic acidosis was studied in rats. L-Methionine-DL-sulfoximine (MSO), an irreversible inhibitor of glutamine synthetase, depressed the renal enzyme activity by 50% but did not impair the recovery from acidosis. Since extrarenal glutamine synthesis was decreased…
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