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2,863 results
  • The impact of cannabis use on intracarotid amobarbital testing. [Case Reports]
    Epilepsy Behav Rep 2019; 12:100328Domen CH, Shrestha A, … Drees C
  • Chronic cannabis use impacts memory functioning, even while users are not acutely intoxicated. The impact of cannabis use on Wada or intracarotid amobarbital testing (IAT) has not previously been described. We reviewed cannabis consumption in epilepsy patients undergoing IAT during pre-surgical work-up. Of 58 patients reviewed, 16 patients (28%) indicated regular use. During IAT, five regular can…
  • Presurgical Functional Cortical Mapping Using Electromagnetic Source Imaging. [Review]
    Front Neurol 2019; 10:628Kreidenhuber R, De Tiège X, Rampp S
  • Preoperative localization of functionally eloquent cortex (functional cortical mapping) is common clinical practice in order to avoid or reduce postoperative morbidity. This review aims at providing a general overview of magnetoencephalography (MEG) and high-density electroencephalography (hdEEG) based methods and their clinical role as compared to common alternatives for functional cortical mapp…
  • Carbonic anhydrase enzymes: Likely targets for inhalational anesthetics. [Journal Article]
    Med Hypotheses 2019; 123:118-124Ozsoy HZ
  • Inhalational anesthetics such as isoflurane, desflurane and halothane are the mainstay medications for surgical procedures; upon inhalation, they produce anesthesia described as reversible unconsciousness with the features of amnesia, sleep, immobility and analgesia. To date, how they produce anesthesia is unknown. This study proposes that carbonic anhydrase enzymes are likely targets mediating t…
  • Intracarotid amobarbital disrupts synchronous and nested oscillatory activity ipsilateral to injection. [Case Reports]
    Epilepsy Behav Case Rep 2018; 10:25-28Young JJ, Friedman JS, … Marcuse LV
  • The mechanism of amobarbital action during the intracarotid amobarbital procedure is poorly understood. We report a patient case who underwent IAP while implanted with bilateral stereo-EEG. We analyzed the spectral power, phase amplitude coupling, and cluster-phase group synchrony during the procedure. Delta and gamma power increased bilaterally. By contrast, phase amplitude coupling increased on…
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