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(amoxicillin clavulanate)
3,990 results
  • Empirical treatment of urinary tract infections: how rational are our guidelines? [Journal Article]
  • JAJ Antimicrob Chemother 2018 Oct 08
  • O'Grady MC, Barry L, … Lucey B
  • CONCLUSIONS: Previous studies determined that a resistance rate of >20% renders an antimicrobial agent unsuitable for use as an empirical treatment option. This study demonstrated that this resistance rate is exceeded in many cases, potentially rendering some antimicrobial agents unsuitable for use as empirical treatment. We suggest that the focus on susceptibility when producing surveillance data to create empirical treatment guidelines may inadvertently camouflage resistance rates. The findings of this study highlight the need for laboratory-guided treatment of UTIs and ideally a pre-emptive sample should be obtained for laboratory investigation prior to commencement of antimicrobial therapy.
  • Human and Animal Bites. [Review]
  • PRPediatr Rev 2018; 39(10):490-500
  • Bula-Rudas FJ, Olcott JL
  • In the United States, nearly 56% of households owned a pet in 2011 according to the 2012 U.S. Pet Ownership & Demographics Sourcebook by the American Veterinary Medical Association. The survey also r...
  • Catheter-Associated Urinary Tract Infection and Obstinate Biofilm Producers. [Journal Article]
  • CJCan J Infect Dis Med Microbiol 2018; 2018:7624857
  • Maharjan G, Khadka P, … Dhungana GR
  • CONCLUSIONS: High antimicrobial resistance was observed in biofilm producers than non-biofilm producers. Of recommended antimicrobial therapies for CAUTIs, ampicillin and amoxicillin-clavulanate were the least active antibiotics, whereas piperacillin/tazobactam and imipenem were found as the most effectual for gram-negative biofilm producer. Likewise, amoxicillin-clavulanate and tetracycline were the least active antibiotics, whereas vancomycin, fosfomycin, piperacillin-tazobactam, and meropenem were found as the most effective antibiotic for Gram-positive biofilm producer. In the limelight, the activity fosfomycin was commendable against both Gram-positive and Gram-negative biofilm producers.
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