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(amphotericin b deoxycholate)
595 results
  • Treatment for HIV-associated cryptococcal meningitis. [Review]
  • CDCochrane Database Syst Rev 2018 07 25; 7:CD005647
  • Tenforde MW, Shapiro AE, … Ford N
  • CONCLUSIONS: In resource-limited settings, one-week AmBd- and 5FC-based therapy is probably superior to other regimens for treatment of HIV-associated cryptococcal meningitis. An all-oral regimen of two weeks 5FC and FLU may be an alternative in settings where AmBd is unavailable or intravenous therapy cannot be safely administered. We found no mortality benefit of combination two weeks AmBd and FLU compared to AmBd alone. Given the absence of data from studies in children, and limited data from high-income countries, our findings provide limited guidance for treatment in these patients and settings.
  • Histoplasmosis in non-endemic North-Western part of India. [Journal Article]
  • IJIndian J Med Microbiol 2018 Jan-Mar; 36(1):61-64
  • Patel AK, Patel KK, … Chakrabarti A
  • CONCLUSIONS: This study highlights that Gujarat and Rajasthan are an endemic region for histoplasmosis, and a systematic study is required to understand epidemiology of the disease. Histoplasmosis should be a differential diagnosis in a patient presenting with adrenal enlargement, lymphadenopathy, oral ulcers and fever of unknown origin in this region.
  • Outcomes of cryptococcosis in renal transplant recipients in a less-resourced health care system. [Journal Article]
  • TITranspl Infect Dis 2018; 20(4):e12910
  • Ponzio V, Camargo LF, … Colombo AL
  • CONCLUSIONS: Graft dysfunction was common in renal transplant recipients with cryptococcosis treated with AMBd. The rate of graft loss rate was high, most frequently in patients with concomitant nephrotoxic conditions. Therefore, the clinical focus should be on the use of less nephrotoxic lipid formulations of amphotericin B in this specific population requiring a polyene induction regimen for treatment of severe cryptococcosis in all health care systems caring for transplantation recipients.
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Noor Asif A Winthrop University Hospital Pellegrini Mark V. MV
  • Amphotericin B deoxycholate belongs to the polyene class of antifungals. It is also known by the name conventional amphotericin B and has been used for the treatment of invasive fungal infections for...
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