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5,356 results
  • Biologics in SAPHO syndrome: A systematic review. [Review]
  • SASemin Arthritis Rheum 2018 Apr 17
  • Daoussis D, Konstantopoulou G, … Liossis SN
  • CONCLUSIONS: In SAPHO patients not responding to conventional treatment, TNF blockers appear to be the first choice. In patients failing TNF blockers, IL-1 inhibitors and biologics targeting the IL-17/IL-23 axis could be used.
  • A Rare but Fascinating Disorder: Case Collection of Patients with Schnitzler Syndrome. [Journal Article]
  • CRCase Rep Rheumatol 2018; 2018:7041576
  • Bashir M, Bettendorf B, Hariman R
  • CONCLUSIONS: Schnitzler syndrome is a rare and underdiagnosed disorder. High suspicion should be maintained in patients with chronic urticaria-like dermatoses, intermittent fevers, and arthralgias. A serum protein electrophoresis and immunofixation should be performed in these patients. The diagnosis is important to recognize as Schnitzler syndrome is associated with malignancy. A lymphoproliferative disorder develops in about 20% of patients at an average of 7.6 years after onset of symptoms. Thus, patients warrant long-term follow-up. IL-1 inhibitors are extremely effective in relieving symptoms and are considered first line therapy.
  • The role of IL-1 in postprandial fatigue. [Journal Article]
  • MMMol Metab 2018 Apr 12
  • Lehrskov LL, Dorph E, … Donath MY
  • CONCLUSIONS: We conclude that IL-1 is involved in the regulation of postprandial fatigue under physiologic conditions in lean and obese individuals. It remains to be shown whether this effect translates into clinical relevant effects.
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