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(ankle clonus)
203 results
  • Spinal Cord Diffuse Midline Glioma in a 4-Year-Old Boy. [Case Reports]
    Child Neurol Open 2019; 6:2329048X19842451Kumar A, Rashid S, … Dure LS
  • CONCLUSIONS: High-grade spinal cord gliomas are very rare but should be considered in the differential diagnosis of pediatric myelopathy. Tissue biopsy is recommended in indeterminate cases to facilitate diagnosis and to guide management.
  • 96 The Cat's Meow? Feline Warning of Imminent Seizures. [Journal Article]
    CNS Spectr 2019; 24(1):222-223Winchester CR, Chioma EB, Hirsch AR
  • CONCLUSIONS: Olfactory emanations occur (Brown, 2011) several hours prior to seizures (Litt, 2009; Rajna, 1997) which the feline may be sensitive due to its superior olfactory ability. The cat's comportment may have induced anxiety in the patient, which then may have precipitated the seizure. The animal thus may be an epileptogenic animal rather than a warning animal. The cat may detect changes in emotion, which predicts the pseudoseizures. On the other hand, the cat may have been acting as an anxiogenic agent, precipitating a pseudoseizure. There may have been a misattribution error, such that she recalled the cat in a position of warning seizures but did not recall when the cat did not warn the seizures. Further investigation in the use of alarm cats as warning for imminent seizures is warranted.
  • GeneReviews®: GTP Cyclohydrolase 1-Deficient Dopa-Responsive Dystonia [BOOK]
    University of Washington, Seattle: Seattle (WA)Adam MP, Ardinger HH, … Amemiya AFurukawa YBOOK
  • GTP cyclohydrolase 1-deficient dopa-responsive dystonia (GTPCH1-deficient DRD) is characterized by childhood-onset dystonia and a dramatic and sustained response to low doses of oral administration of levodopa. This disorder typically presents with gait disturbance caused by foot dystonia, later development of parkinsonism, and diurnal fluctuation of symptoms (aggravation of symptoms toward the e…
  • A novel mutation of SGSH and clinical features analysis of mucopolysaccharidosis type IIIA. [Case Reports]
    Medicine (Baltimore) 2018; 97(52):e13758Li X, Xiao R, … Huang Y
  • CONCLUSIONS: The common clinical manifestations of MPS IIIA were rapid developmental regression, seizures, cerebral atrophy, and thickened calvarial diploe. The results showed that the c.630 G > T was likely pathogenic according to bioinformatics analysis, which probably was a novel mutation. This study reports 1 case of MPS IIIA with some clinical features as determined via clinical and genetic analysis, and found a new mutation in the SGSH gene.
  • StatPearls: Clonus [BOOK]
    StatPearls Publishing: Treasure Island (FL) Zimmerman Barret B Wake Forest Hubbard John B. JB Wake Forest Baptist Health BOOK
  • Clonus is a rhythmic, oscillating, stretch reflex, the cause of which is not totally known; however, it relates to lesions in upper motor neurons and therefore is generally accompanied by hyperreflexia.  Therefore, clonus is used as part of the neurological physical exam to evaluate the status of a patient’s nervous system.  It can be evaluated in many joints but is most commonly seen in the ankl…
  • Development of a Clonus Management System: A Case Study of Sit-To-Stand Learning in a Stroke Patient. [Journal Article]
    Conf Proc IEEE Eng Med Biol Soc 2018; 2018:5958-5961Shiraishi R, Kawamoto H, Sankai Y
  • This paper proposes a new clonus management system that integrates sit-to-stand (STS) learning with informatics and physical methods. Clonus is an involuntary muscle spasm, which often interferes with motor learning or the training of chronic patients. A conventional ankle-foot orthosis makes it difficult for patients to control the onset of clonus or to improve it. A new system with an original …
  • A Rare Case of Klinefelter Syndrome Accompanied by Spastic Paraplegia and Peripheral Neuropathy. [Case Reports]
    Intern Med 2019; 58(3):437-440Sasaki R, Ohta Y, … Abe K
  • Klinefelter syndrome is a chromosomal disorder with a typical karyotype of 47, XXY, accompanied by various neurological symptoms. We herein report the first case of Klinefelter syndrome with a rare mosaic form of 47, XXY and 48, XXXY, combined with both spastic paraplegia and peripheral motor neuropathy. This case showed spasticity and hyperreflexia with pathological reflexes and ankle clonus as …
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