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1,350,567 results
  • Rapid disappearance of both severe atopic dermatitis and cold urticaria induced by dupilumab. [Letter]
    Clin Exp Dermatol 2019Ferrucci S, Benzecry V, … Asero R
  • Dupilumab is a human monoclonal IgG4 antibody that inhibits IL-4 and IL-13 signalling by binding specifically to the IL-4Rα subunit, shared by both the IL4 and IL-13 receptor complexes (1) recently introduced for the treatment of severe atopic dermatitis (AD). We report a case of severe AD associated with cold urticaria that healed shortly after starting Dupilumab therapy. This article is protect…
  • Evolution of multi-functional capillary electrophoresis for high-efficiency selection of aptamers. [Review]
    Biotechnol Adv 2019; :107432Zhu C, Yang G, … Qu F
  • Aptamers have drawn considerable attention as newly emerging molecular recognition elements in clinical diagnostics, drug delivery, therapeutics, environmental monitoring, and food safety analyses. As the in vitro screening antibody analogs, aptamers are enabled to recognize various types of targets with high affinity and specificity like or even superior to antibodies. However, the restrictions …
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