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Unbound Medicine.
(antifungals)
192,427 results
  • Mortality and risk factor analysis for Candida blood stream infection: A three-year retrospective study. [Journal Article]
    J Mycol Med. 2020 Jun 25 [Online ahead of print]Muderris T, Kaya S, … Yurtsever Gul S
  • CONCLUSIONS: Dialysis and concurrent bacteremia are strong predictors of mortality in 30 days within patients with candidemia, whereas follow-up blood cultures have a protective role with lower mortality rates. In our study, the most important source of candidemia was catheter, and C. parapsilosis was the most common causative agent. The catheter was removed in almost all patients and the mortality rate was almost one third among these patients.
  • Anticandidal activity of Lactobacillus spp. in the presence of galactosyl polyols. [Journal Article]
    Microbiol Res. 2020 Jun 27; 240:126540.Lipinska-Zubrycka L, Klewicki R, … Klewicka E
  • Yeasts have a substantial impact on the contamination and loss of food. In this study, we applied bacteria of the genus Lactobacillus as natural biopreservatives. Anticandidal strains of bacteria were selected from among 60 strains of bacteria grown which were each with nine polyols or galactosyl polyols. Polyols and galactosyl polyols can act as prebiotics for lactic acid bacteria and can enhanc…
  • Contending charcoal rot disease of mungbean by employing biocontrol Ochrobactrum ciceri and zinc. [Journal Article]
    Physiol Mol Biol Plants. 2020 Jul; 26(7):1385-1397.Shoaib A, Ali H, … Awan ZA
  • Role of rhizobacteria and zinc (Zn) was investigated in the management of charcoal rot disease in mungbean [Vigna radiata (L.) Wilczek] caused by Macrophomina phaseolina (Tassi) Goid. In vitro, screening tests with eight rhizobacteria [Bacillus subtilis (FCBP-0324), B. subtilis (FCBP-0189), Rhizobacter daucus (FCBP-0450), Azospirillum brasilense (FCBP-0025), Azospirillum lipoferum (FCBP-0022), Ps…
  • Antimicrobial activity of Epsilon-Poly-L-lysine against phytopathogenic bacteria. [Journal Article]
    Sci Rep. 2020 Jul 09; 10(1):11324.Rodrigues B, Morais TP, … Goulart LR
  • Antimicrobial peptides (AMPs) are components of immune defense in many organisms, including plants. They combat pathogens due to their antiviral, antifungal and antibacterial properties, and are considered potential therapeutic agents. An example of AMP is Epsilon-Poly-L-lysine (EPL), a polypeptide formed by ~ 25 lysine residues with known antimicrobial activity against several human microbial pa…
  • Fluconazole-induced acute generalized exanthematous pustulosis. [Case Reports]
    Am J Emerg Med. 2020 Jun 28 [Online ahead of print]Saliba E, Chrabieh R, Tannous Z
  • Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction usually caused by drugs. The annual incidence is one to five cases per million. It is characterized by an acute febrile episode, accompanied by numerous small primarily non-follicular, sterile pustules arising within large areas of edematous erythema. There have been several case reports to date of AGEP …
  • Molecular Methods for the Diagnosis of Invasive Candidiasis. [Review]
    J Fungi (Basel). 2020 Jul 06; 6(3)Camp I, Spettel K, Willinger B
  • Invasive infections caused by members of the genus Candida are on the rise. Especially patients in intensive care units, immunocompromised patients, and those recovering from abdominal surgery are at risk for the development of candidemia or deep-seated candidiasis. Rapid initiation of appropriate antifungal therapy can increase survival rates significantly. In the past, most of these infections …
  • In vitro activity of isavuconazole against clinically isolated yeasts from Chile. [Journal Article]
    Braz J Microbiol. 2020 Jul 07 [Online ahead of print]Álvarez Duarte E, Salas V
  • Isavuconazole is the last antifungal agent approved by the FDA and available for treatment of fungal infections. In the present study, the in vitro activity of isavuconazole against several yeasts was investigated. Two hundred forty-six isolates were included: 64 Candida albicans, 53 Candida parapsilosis sensu stricto, 48 Cryptococcus neoformans species complex, 27 C. glabrata sensu stricto, 17 C…
  • Synthesis and Antimicrobial Activity of Novel 4-Hydroxy-2-quinolone Analogs. [Journal Article]
    Molecules. 2020 Jul 04; 25(13)Khamkhenshorngphanuch T, Kulkraisri K, … Khotavivattana T
  • Alkyl quinolone has been proven to be a privileged scaffold in the antimicrobial drug discovery pipeline. In this study, a series of new 4-hydroxy-2-quinolinone analogs containing a long alkyl side chain at C-3 and a broad range of substituents on the C-6 and C-7 positions were synthesized. The antibacterial and antifungal activities of these analogs against Staphylococcus aureus, Escherichia col…
  • Survey and Identification of Date Palm Pathogens and Indigenous Biocontrol Agents. [Journal Article]
    Plant Dis. 2020 Jul 06 [Online ahead of print]Nishad R, Ahmed TA
  • Fungal diseases are considered a major threat to plant growth and productivity. However, some beneficial fungi growing in the same environment protect plants from various pathogens, either by secreting antifungal metabolites or by stimulating the host immune defense mechanism. Date palms are susceptible to several fungal pathogens. Nevertheless, information on the pathogenic fungal distribution i…
  • Fungal Quorum-Sensing Molecules: A Review of Their Antifungal Effect against Candida Biofilms. [Review]
    J Fungi (Basel). 2020 Jul 02; 6(3)Kovács R, Majoros L
  • The number of effective therapeutic strategies against biofilms is limited; development of novel therapies is urgently needed to treat a variety of biofilm-associated infections. Quorum sensing is a special form of microbial cell-to-cell communication that is responsible for the release of numerous extracellular molecules, whose concentration is proportional with cell density. Candida-secreted qu…
  • Antifungal Resistance Regarding Malassezia pachydermatis: Where Are We Now? [Review]
    J Fungi (Basel). 2020 Jun 25; 6(2)Peano A, Johnson E, … Pasquetti M
  • Malassezia pachydermatis is a yeast inhabiting the skin and ear canals in healthy dogs. In the presence of various predisposing conditions it can cause otitis and dermatitis, which are treated with multiple antifungal agents, mainly azole derivatives. This manuscript aims to review the available evidence regarding the occurrence of resistance phenomena in this organism. Various findings support t…
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