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1,302,907 results
  • StatPearls: Balloon Sinuplasty [BOOK]
    StatPearls Publishing: Treasure Island (FL) Lofgren Daniel D McLaren Oakland Hospital Shermetaro Carl C Mclaren Oakland Hospital BOOK
  • Since the Federal Drug Administration (FDA) approval for nasal sinus use in 2005, balloon sinuplasty (BSP) has continued to grow in popularity among otolaryngologists as a minimally invasive way to treat patients suffering from chronic rhinosinusitis (CRS).[1][2][3] The idea of using balloon dilation to open an anatomic structure is not a new concept, as cardiac surgeons have used similar techniq…
  • StatPearls: Physiology, Antibody [BOOK]
    StatPearls Publishing: Treasure Island (FL) Aziz Mehwish M Windsor University School of Medicine Iheanacho Franklin F Value Institute, Christiana Care Health System BOOK
  • Antibodies are naturally produced by plasma cells within the human body to mediate an adaptive immune response against invading pathogens. There are five predominant antibodies produced, each specialized to execute certain functions. Antibodies gain the ability to identify a diverse range of antigens by genetic recombination of different elements of its structure and while the affinity for a spec…
  • StatPearls: Biochemistry, HLA Antigens [BOOK]
    StatPearls Publishing: Treasure Island (FL) Nordquist Helen H University of New Mexico Jamil Radia T. RT Allama Iqbal Medical College BOOK
  • Human leukocyte antigens (HLA) are genes in major histocompatibility complexes (MHC) that help code for proteins that differentiate between self and non-self. They play a significant role in disease and immune defense. They are beneficial to the immune system, but can also have detrimental effects. Some of the immune system effects are the interaction with complement, the cytotoxic effect of T ce…
  • The Pathogenesis of Primary Biliary Cholangitis: A Comprehensive Review. [Journal Article]
    Semin Liver Dis 2019Lleo A, Leung PSC, … Gershwin EM
  • Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease characterized by autoimmune destruction of small to medium size intrahepatic bile ducts. The etiology of PBC remains unknown and pathogenesis features immune-mediated biliary injury, alongside the consequences of chronic cholestasis. PBC is strongly associated with the loss of immune tolerance against mitochondrial antigens …
  • Anti-p53 autoantibody in blood as a diagnostic biomarker for colorectal cancer: a meta-analysis. [Review]
    Scand J Immunol 2019; :e12829Liu S, Tan Q, … Han X
  • Serum autoantibodies against tumor-associated antigens are promising biomarkers for diagnosis of cancer. This review summarizes the available evidence pertaining to the diagnostic potential of autoantibodies studied in the context of colorectal cancer (CRC). A systematic literature search was conducted in three databases (PubMed, Cochrane Library, and Embase). Data pertaining to a total of 145 au…
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