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(antigen processing)
40,976 results
  • SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression. [Journal Article]
    Neoplasia 2019; 21(10):945-962Alam A, Taye N, … Chattopadhyay S
  • Down-regulation or loss of MHC class I expression is a major mechanism used by cancer cells to evade immunosurveillance and increase their oncogenic potential. MHC I mediated antigen presentation is a complex regulatory process, controlled by antigen processing machinery (APM) dictating immune response. Transcriptional regulation of the APM that can modulate gene expression profile and their corr…
  • Infant Facial Paralysis Associated with Epstein-Barr Virus Infection. [Journal Article]
    Am J Case Rep 2019; 20:1216-1219Álvarez-Argüelles ME, Rojo-Alba S, … Melón García S
  • CONCLUSIONS: Whilst the most common cause of facial paralysis is idiopathic paralysis, such problems of the facial nerve may have many origins, including an infectious nature such as infection with viral agents. Rapid determination of the etiology of the problem allows the most appropriate management of the condition and quick follow-up to be implemented, which is essential for the evaluation of treatment response and the avoidance of permanent consequences.
  • Preservation of cell-based immunotherapies for clinical trials. [Review]
    Cytotherapy 2019Li R, Johnson R, … Hubel A
  • In the unique supply chain of cellular therapies, preservation is important to keep the cell product viable. Many factors in cryopreservation affect the outcome of a cell therapy: (i) formulation and introduction of a freezing medium, (ii) cooling rate, (iii) storage conditions, (iv) thawing conditions and (v) post-thaw processing. This article surveys clinical trials of cellular immunotherapy th…
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