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8 results
  • Biological assessment of ozone therapy on experimental oral candidiasis in immunosuppressed rats. [Journal Article]
    Biochem Biophys Rep 2018; 15:57-60Amin LE
  • Immunosuppressive drugs can compromise local or general defense mechanisms and can lead to oral candidiasis. Ozone therapy has a wide range of applications in almost every field of dentistry. Its unique properties include immunostimulant, analgesic, antihypnotic, detoxicating, and antimicrobial actions. Sixty male healthy rats were immunosuppressed with dexamethasone in their drinking water one w…
  • Mildronate exerts acute anticonvulsant and antihypnotic effects. [Journal Article]
    Behav Pharmacol 2010; 21(5-6):548-55Zvejniece L, Svalbe B, … Dambrova M
  • The effects of mildronate [3-(2,2,2-trimethylhydrazinium) propionate], an inhibitor of L-carnitine biosynthesis and an anti-ischaemic drug, were examined in various in-vivo conditions to investigate the neuropharmacological profile after acute administration. Mildronate (200 mg/kg, acute intraperitoneal administration) exerted anticonvulsant activity in a chemoconvulsant pentylenetetrazole-induce…
  • [Mechanism of drug dependency: answers to the questions of KATO]. [Journal Article]
    Seishin Shinkeigaku Zasshi 2000; 102(6):562-7Takigawa M
  • The complicated mechanisms of drug dependency were discussed from the perspective of a reward, especially the perspective of psychic dependency of the brain. In Kato's article, the following questions were raised. (1) Improper usage of terminology in describing the objective pharmacological behavior and describing the subjective psychic experience, e.g. the term "obsessional comfort". (2) The enh…
  • Induction of methamphetamine-specific antibody using biodegradable carboxymethyl-chitin. [Journal Article]
    Anal Biochem 1987; 161(1):117-22Tokura S, Hasegawa O, … Takatori T
  • Induction of a specific antibody for methamphetamine, an antihypnotic drug, has been studied using carboxymethyl-chitin (CM-chitin) as a hapten carrier. The hapten-specific antiserum was induced by only a couple of hypodermal injections every 2 weeks. Inhibition of antigen-antibody complex formation was linearly related to methamphetamine concentration in the range 0.5 to 50 ng/50 microliter when…
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