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19,498 results
  • Clinical Retrospective Analysis of Interstitial Lung Disease Patients Associated with Pulmonary Hypertension. [Journal Article]
    Med Sci Monit 2019; 25:7763-7769Lv H, Liu J, … Zhang J
  • CONCLUSIONS: Pulmonary hypertension occurred in 25% of the 182 interstitial lung disease patients and was negatively associated with deteriorated lung functions (specifically VC%, FVC%, and DLCO parameters). ANA level was not associated with the prognosis of pulmonary hypertension of patients with interstitial lung disease, and it did not significantly affect the correlation between PASP and pulmonary functions. Thus, ANA level did not seem to be a necessary indicator of pulmonary hypertension, and a more effective treatment method for pulmonary hypertension of patients with interstitial lung disease is urgently needed.
  • A Multicenter Analysis of Subjectivity of Indirect Immunofluorescence Test in Antinuclear Antibody Screening. [Journal Article]
    Arch Rheumatol 2019; 34(3):326-333Turan Faraşat V, Ecemiş T, … Şanlidağ T
  • CONCLUSIONS: Significant differences may be observed among laboratories in terms of qualitative results, patterns, and semi-quantitative determination of the fluorescence intensity in the ANA-IIF testing, particularly at low fluorescence intensity levels and in those with speckled patterns. In case of any discrepancy between ANA-IIF test and clinical prediagnosis, the test should be repeated in another laboratory, if necessary.
  • [Late-age onset systemic sclerosis]. [Journal Article]
    Wiad Lek 2019; 72(9 cz 1):1683-1686Wielosz E
  • Systemic sclerosis is a multi-organ connective tissue disease characterised by dysfunction and impaired morphology of the blood vessels with non-specific inflammation and progressive fibrosis. In the majority of cases, the onset is observed between 30-50 years of age; in many cases, however, the diagnosis is established in patients < 20 years of age or > 75 years of age. The course of late-onset …
  • Recent advances in the workup and management of Raynaud's phenomenon. [Journal Article]
    Pol Arch Intern Med 2019Lis-Święty A
  • Raynaud's phenomenon (RP) is defined as recurrent, reversible episodes of vasospasm involving peripheral small vessels, typically in the fingers and toes. Primary RP (idiopathic RP) is common, occurring in circa 5% of the general population, and is usually benign. Secondary RP accounts for 10-20% of all RP cases and may be associated with complications such as tissue loss, ulcers, and gangrene. S…
  • Hemophagocytic Syndrome as an Initial Presentation of Systemic Lupus Erythematosus: A Case Report. [Case Reports]
    Cureus 2019; 11(7):e5261AlSheef M, Zaidi ARZ, … Mian A
  • Hemophagocytic syndrome (HPS) is an uncommon potentially life-threatening hematological disorder characterized by fever, pancytopenia, lymphadenopathy, and activation of macrophages, which can be associated with various diseases. HPS brings significant diagnostic and therapeutic challenges, especially if it is the presenting manifestation of an autoimmune disorder, which is uncommon. We present a…
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