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(antipyresis)
211 results
  • A novel pH-controlled hydrogen sulfide donor protects gastric mucosa from aspirin-induced injury. [Journal Article]
    J Cell Mol Med 2017; 21(10):2441-2451Yang CT, Lai ZZ, … Zhang H
  • Hydrogen sulphide (H2 S) serves as a vital gastric mucosal defence under acid condition. Non-steroidal anti-inflammatory drugs (NSAIDs) are among widely prescribed medications with effects of antipyresis, analgesia and anti-inflammation. However, their inappropriate use causes gastric lesions and endogenous H2 S deficiency. In this work, we reported the roles of a novel pH-controlled H2 S donor (…
  • Anti-allergic effect of Artemisia extract in rats. [Journal Article]
    Exp Ther Med 2016; 12(2):1130-1134Deng Y, Liu Z, Geng Y
  • Artemisia apiacea (also known as Artemisia annua L) is a herb commonly used in traditional Chinese medicine. In the early 1970s, artemisinin was isolated and identified as the active antimalarial ingredient, and thereafter, A. apiacea and artemisinin have been studied extensively, such as anti-inflammation and antipyresis, antibacteria, antiparasitic and immunosuppression effects of A. apiacea ex…
  • Pharmacokinetic properties of intramuscular versus oral syrup paracetamol in Plasmodium falciparum malaria. [Randomized Controlled Trial]
    Malar J 2016; 15:244Wattanakul T, Teerapong P, … Tarning J
  • CONCLUSIONS: Paracetamol plasma concentrations after oral syrup and intramuscular administration in patients with acute falciparum malaria were described successfully by a two-compartment disposition model. Relative oral bioavailability compared to intramuscular dosing was estimated as 84.4 % (95 % CI 68.2-95.1 %). Dosing simulations showed that a loading dose followed by six-hourly dosing intervals reduced the time delay to reach therapeutic drug levels after both routes of administration. The safety and efficacy of loading dose paracetamol antipyretic regimens now needs to be established in larger studies.
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