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64 results
  • Use of pharmaceuticals in noninvasive cardiovascular diagnosis. [Review]
    Heart Dis. 2002 Sep-Oct; 4(5):315-30.Meisner JS, Shirani J, … Frishman WH
  • A number of pharmaceuticals are employed as diagnostic agents for cardiovascular diseases. Four groups of agents are reviewed here: 1) vasoactive substances employed as adjuncts to physical maneuvers in diagnosis of structural heart disease; 2) vasodilators used to produce heterogeneity of coronary flow; 3) sympathomimetic agents simulating the effects of exercise on the heart for the purpose of …
  • Pharmacologic interventions in nuclear radiology: indications, imaging protocols, and clinical results. [Review]
    Radiographics. 2002 May-Jun; 22(3):477-90.Saremi F, Jadvar H, Siegel ME
  • Nuclear radiology is valuable in assessing pathophysiology of a variety of organ systems. Pharmacologic interventions are often employed in radionuclide imaging to monitor the physiologic changes, which in turn facilitate the diagnosis. Metoclopramide, erythromycin, and cisapride have been used for gastric emptying studies. To overcome false-negative results, cimetidine, pentagastrin, and glucago…
  • Pharmacological stress agents for evaluation of ischemic heart disease. [Review]
    Int J Cardiol. 2001 Dec; 81(2-3):157-67.Ali Raza J, Reeves WC, Movahed A
  • Ischemic heart disease is the leading cause of death in the developed countries for those older than 65 years of age. In patients suspected to have coronary artery disease a stress test should be performed to identify the vulnerability of the myocardium to ischemia. As a rule of thumb, the evaluation of coronary artery disease is best done by exercise stress test. In patients who are not able to …
  • Arbutamine stimulation detects viable myocardium 4 weeks after coronary occlusion. [Journal Article]
    J Am Soc Echocardiogr. 2001 Feb; 14(2):138-48.Kisanuki A, Segar DS, … Sawada SG
  • At low doses, dobutamine has potent inotropic, but limited chronotropic, effects-properties that may be necessary for detection of hibernating myocardium. The efficacy of other catecholamines, which have more closely coupled inotropic and chronotropic effects, for the detection of viable myocardium is unknown. This study evaluated the efficacy of arbutamine, a catecholamine with potent chrono-tro…
  • Diagnostic efficacy of SonoVue. [Review]
    Am J Cardiol. 2000 Aug 17; 86(4A):19G-24G.Bokor D
  • SonoVue is a second-generation ultrasound contrast agent consisting of phospholipid-stabilized microbubbles filled with sulfur hexafluoride, with outstanding stability and resistance to pressure. The efficacy of SonoVue (0.5, 1, 2, 4 mL) was compared with Albunex (doses 0.08 and 0.22 mL/kg) in patients with suspected ischemic disease and suboptimal endocardial-border delineation on unenhanced ech…
  • [Stress echocardiography]. [Review]
    Z Kardiol. 2000; 89 Suppl 1:78-85.Nixdorff U
  • Within the last decade of this millennium, stress echocardiography has been established for the diagnosis and follow-up of coronary artery disease. The basis is the technical development of the echo machines: first, the improved echocardiographic resolution and, second, the digital image storage of a whole cineloop, which may be interpreted frame-by-frame in an ECG synchronized manner for several…
  • Comparative physiological study of arbutamine with exercise in humans. [Controlled Clinical Trial]
    Clin Sci (Lond). 2000 Apr; 98(4):489-94.Lovell SL, Maguire SM, … Nicholls DP
  • Pharmacological stress testing may be used in the diagnosis of coronary artery disease when there are contra-indications to the use of conventional exercise protocols. The responses to such testing using arbutamine and to conventional treadmill exercise were compared in eight patients. Respiratory gas analysis and cardiovascular observations were performed during both tests. For an equivalent inc…
  • Pharmacological stress testing. [Review]
    Semin Nucl Med. 1999 Oct; 29(4):298-318.Travain MI, Wexler JP
  • Pharmacological stress in conjunction with radionuclide myocardial perfusion imaging has become a widely used noninvasive method of assessing patients with known or suspected coronary artery disease. In the United States, over one third of perfusion imaging studies are performed with pharmacological stress. Pharmacological stress agents fall into two categories: coronary vasodilating agents such …
  • Pharmacologic stress echocardiography. Dobutamine and arbutamine stress testing. [Review]
    Cardiol Clin. 1999 Aug; 17(3):461-79, viii.Orsinelli DA, Daniels CJ
  • Pharmacologic stress testing is an important noninvasive method for evaluating patients with known or suspected coronary artery disease who are unable to adequately exercise. Pharmacologic stress echocardiography using dobutamine has been developed over the last 10 to 15 years as an alternative to vasodilator stress testing using nuclear perfusion imaging. As experience has grown, digital subtrac…
  • [Cardiology in 1997]. [Journal Article]
    Cas Lek Cesk. 1998 Oct 05; 137(19):585-9.Jerie P
  • A review of the most important findings published during 1997 in cardiovascular papers is presented: Chlamydia pneumoniae was recognised as a potential risk factor for coronary artery disease (CAD) and possible pathogenic agent for valvular aortic stenosis. Valvular changes similar to the valvular disease reported after ergotamine and methylsergide were also detected in obese women treated with a…
  • Hemodynamic effects of arbutamine. [Journal Article]
    Am J Cardiol. 1998 Sep 01; 82(5):699-702, A9.Ogilby JD, Molk B, Iskandrian AE
  • This study examined the hemodynamic effects of arbutamine, a synthetic catecholamine, in 12 patients with and 7 patients without coronary artery disease. Arbutamine produced a balanced positive inotropic (increase in left ventricular dp/dt) and chronotropic effect (increase in heart rate).
  • A comparison of adenosine and arbutamine for myocardial perfusion imaging. [Journal Article]
    Eur J Nucl Med. 1998 Apr; 25(4):394-400.Anagnostopoulos C, Pennell D, … Underwood R
  • We have compared our standard stress protocol (adenosine combined with exercise) with the new stress agent arbutamine, for thallium-201 myocardial perfusion imaging (MPI) in order to assess the comparative value of arbutamine. We studied 23 patients referred for MPI, and each patient had two studies (18 males, median age 66 years, five with previous myocardial infarction). Uptake scores were assi…
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