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40 results
  • Drugs and Lactation Database (LactMed): Heparin [BOOK]
    National Library of Medicine (US): Bethesda (MD)BOOK
  • Although heparin itself has not been studied, low molecular weight heparins (e.g., dalteparin, enoxaparin) are not excreted into breastmilk in clinically relevant amounts. Because heparin has an even higher molecular weight of 3000 to 30,000 daltons, it would not be expected to be appreciably excreted into breastmilk or absorbed by the infant. No special precautions are required.[1]
  • Heparin Oligosaccharides Have Antiarrhythmic Effect by Accelerating the Sodium-Calcium Exchanger. [Journal Article]
    Front Cardiovasc Med 2018; 5:67de Godoy CMG, Vasques ÊR, … Tersariol ILDS
  • Background: Blockage of the Na+/Ca2+ exchanger (NCX) is used to determine the role of NCX in arrhythmogenesis. Trisulfated heparin disaccharide (TD) and Low Molecular Weight Heparins (LMWHs) can directly interact with the NCX and accelerate its activity. Objective: In this work, we investigated the antiarrhythmic effect of heparin oligosaccharides related to the NCX activity. Methods: The effe…
  • Pharmacologic profile of certoparin. [Journal Article]
    Expert Opin Investig Drugs 1999; 8(3):315-27Jeske W, Wolf H, … Fareed J
  • The low molecular weight heparins (LMWHs) are now not only used for the prophylaxis and treatment of deep vein thrombosis (DVT), but also for the management of acute coronary syndromes. Beside these approved usages, the LMWHs have been developed for indications such as thrombotic and ischaemic stroke, cancer-associated thrombotic and vascular disorders, Alzheimer's disease and a variety of inflam…
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