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19,702 results
  • Precapillary sphincters maintain perfusion in the cerebral cortex. [Journal Article]
    Nat Commun 2020; 11(1):395Grubb S, Cai C, … Lauritzen M
  • Active nerve cells release vasodilators that increase their energy supply by dilating local blood vessels, a mechanism termed neurovascular coupling and the basis of BOLD functional neuroimaging signals. Here, we reveal a mechanism for cerebral blood flow control, a precapillary sphincter at the transition between the penetrating arteriole and first order capillary, linking blood flow in capillar…
  • Florbetapir Regional Distribution in Cerebral Amyloid Angiopathy and Alzheimer's Disease: A PET Study. [Journal Article]
    J Alzheimers Dis 2020Planton M, Saint-Aubert L, … Pariente J
  • CONCLUSIONS: Patients with CAA-ICH had a lower global florbetapir PET burden than patients with MCI-AD. Relative florbetapir retention in the posterior regions tented to be higher in CAA patients in region-based analysis but was no statistically different between groups. Investigation on differences in amyloid deposits distribution between groups required a fine-grained voxel-wise analysis. In future studies, selective amyloid tracers are needed to differentiate vascular from parenchymal amyloid.
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