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(as treated analysis)
556,363 results
  • Tissue-guided LASSO for prediction of clinical drug response using preclinical samples. [Journal Article]
    PLoS Comput Biol 2020; 16(1):e1007607Huang EW, Bhope A, … Emad A
  • Prediction of clinical drug response (CDR) of cancer patients, based on their clinical and molecular profiles obtained prior to administration of the drug, can play a significant role in individualized medicine. Machine learning models have the potential to address this issue but training them requires data from a large number of patients treated with each drug, limiting their feasibility. While …
  • Synthetic apolipoprotein A-I mimetic peptide 4F protects hearts and kidneys after myocardial infarction. [Journal Article]
    Am J Physiol Regul Integr Comp Physiol 2020Moreira RS, Irigoyen MC, … Andrade L
  • Patients undergoing coronary angiography after myocardial infarction (MI) often develop cardiac and renal dysfunction. We hypothesized that the apolipoprotein A-I mimetic peptide 4F (hereafter, 4F) would prevent those complications. Male Wistar rats were fed a high-cholesterol diet for 8 days. The rats were then anesthetized with isoflurane and randomly divided into five groups a control group (s…
  • [Characteristics of pancreatic mucinous cystic neoplasm in patients treated at a National Hospital in Peru]. [Journal Article]
    Rev Peru Med Exp Salud Publica 2019 Oct-Dec; 36(4):670-675Revoredo-Rego F, Reaño-Paredes G, … Landeo-Aliaga I
  • In order to analyze the clinical, pathological, and surgical characteristics of pancreatic mucinous cystic neoplasm (MCN), an analysis of the patients from the Pancreas, Spleen, and Retroperitoneal Surgery Service of the Guillermo Almenara Irigoyen National Hospital in Lima, Peru, was performed from January 2009 to October 2018. The presence of ovarian stroma was used as a diagnostic criterion fo…
  • [Genetic diagnosis of patients with primary agammaglobulinemia treated at third level peruvian centers]. [Journal Article]
    Rev Peru Med Exp Salud Publica 2019 Oct-Dec; 36(4):664-669Matos-Benavides E, García-Gomero D, … Aldave-Becerra J
  • Primary agammaglobulinemia result from specific alterations in B cells, which lead to low antibody production. Diagnostic suspicion is established with a history of repeated infections, low immunoglobulins, and absence of CD19+ B lymphocytes. The diagnosis is confirmed by genetic analysis and the detection of a mutation linked to the X or autosomal recessive or dominant chromosome. In Peru, there…
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