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43,113 results
  • The Cerebellar Cognitive Affective/Schmahmann Syndrome: a Task Force Paper. [Review]
    Cerebellum 2019Argyropoulos GPD, van Dun K, … Schmahmann JD
  • Sporadically advocated over the last two centuries, a cerebellar role in cognition and affect has been rigorously established in the past few decades. In the clinical domain, such progress is epitomized by the "cerebellar cognitive affective syndrome" ("CCAS") or "Schmahmann syndrome." Introduced in the late 1990s, CCAS reflects a constellation of cerebellar-induced sequelae, comprising deficits …
  • Structural analysis of glutathionyl hemoglobin using native mass spectrometry. [Journal Article]
    J Struct Biol 2019Muralidharan M, Mitra A, … Kumar Mandal A
  • Glutathionylation is an example of reversible post-translation modification of proteins where free and accessible cysteine residues of proteins undergo thiol-disulfide exchange with oxidized glutathione (GSSG). In general, glutathionylation occurs under the condition of elevated oxidative stress in vivo. In human hemoglobin, Cys93 residue of β globin chain was found to undergo this oxidative modi…
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