Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.
(ataxia)
44,894 results
  • Misdiagnosis of lamotrigine toxicity as posterior circulation transient ischemic attack or stroke. [Journal Article]
    Epilepsy Behav. 2020 Jul 08; 111:107284.Ramey P, Osborn M, … Abou-Khalil B
  • CONCLUSIONS: Emergency departments will frequently call a stroke alert for patients taking LTG and presenting with symptoms consistent with LTG toxicity, particularly in seniors at greater risk of stroke. This adds not only expense but also radiation and contrast exposure from computed tomography (CT) studies. We recommend that a rapid LTG assay be made available and always ordered in patients receiving LTG, avoiding the considerable expense of an unnecessary stroke evaluation.
  • The cerebellar nuclei and dexterous limb movements. [Review]
    Neuroscience. 2020 Jul 08 [Online ahead of print]Thanawalla AR, Chen AI, Azim E
  • Dexterous forelimb movements like reaching, grasping, and manipulating objects are fundamental building blocks of the mammalian motor repertoire. These behaviors are essential to everyday activities, and their elaboration underlies incredible accomplishments by human beings in art and sport. Moreover, the susceptibility of these behaviors to damage and disease of the nervous system can lead to de…
  • Chronic immune sensory polyradiculopathy (CISP): First juvenile case description. [Letter]
    Neurol Sci. 2020 Jul 10 [Online ahead of print]Sotgiu S, Minutolo A, … Nobile-Orazio E
  • In its typical presentation, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) occurs more often in old males as a progressive/recurrent motor and sensory nerve dysfunction with tendon areflexia. However, CIDP has also atypical clinical presentations, including pure sensory neuropathies, among which chronic immune sensory polyradiculopathy (CISP) accounts for only 0.5% of all CIDP,…
  • Update on DNA-Double Strand Break Repair Defects in Combined Primary Immunodeficiency. [Review]
    Curr Allergy Asthma Rep. 2020 Jul 09; 20(10):57.Slatter MA, Gennery AR
  • The most serious DNA damage, DNA double strand breaks (DNA-dsb), leads to mutagenesis, carcinogenesis or apoptosis if left unrepaired. Non-homologous end joining (NHEJ) is the principle repair pathway employed by mammalian cells to repair DNA-dsb. Several proteins are involved in this pathway, defects in which can lead to human disease. This review updates on the most recent information available…
  • Acute ophthalmoplegia in a patient with anti-GQ1b antibody and chronic facial diplegia. [Journal Article]
    BMJ Case Rep. 2020 Jul 09; 13(7)Du FH, Yerevanian A, Shtrahman M
  • A 56-year-old man with a remote history of bilateral recurrent facial palsies presented with a week of ophthalmoplegia with intact deep tendon reflexes and lack of ataxia, cerebrospinal fluid with albuminocytologic dissociation and elevated serum anti-ganglioside Q1b (GQ1b) IgG antibody. We diagnosed the patient with acute ophthalmoplegia without ataxia, a condition under the spectrum of anti-GQ1…
  • StatPearls: Cinchonism [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Bykowski Adam A Mclaren Health System Logan Timothy D. TD Michigan State University College of Osteopathic Medicine BOOK
  • Cinchonism is a collection of symptoms stemming from the ingestion of quinoline derivatives and its subsequent neural, retinal, and auditory toxicity. Ingestion of quinoline derivatives can produce a multitude of detrimental effects. Cinchonism is a subset of these effects originally believed to be primarily neurally mediated. This definition does not include the pro-arrhythmic properties of thes…
  • StatPearls: Subacute Combined Degeneration of the Spinal Cord [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Qudsiya Zainab Z Gulf Medical University, Ajman De Jesus Orlando O University of Puerto Rico, Medical Sciences Campus, Neurosurgery Section BOOK
  • Subacute combined degeneration of the spinal cord is a neurological complication of vitamin B12 (cobalamin) deficiency. A deficiency of vitamin B12 can occur as a result of nutritional deficiency, reduced absorption due to altered gastrointestinal anatomy or function, or due to the intake of certain drugs. Subacute combined degeneration is characterized by degeneration of the dorsal columns and t…
  • StatPearls: Dysdiadochokinesia [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Rocha Cabrero Franklyn F University of Miami/Jackson Memorial Hospital De Jesus Orlando O University of Puerto Rico, Medical Sciences Campus, Neurosurgery Section BOOK
  • Dysdiadochokinesia (diadochokinesia) is the inability to perform rapid alternating muscle movements. These can be quick, synchronous, and can include pronation/supination, fast finger tapping, opening and closing of the fists, and foot tapping. It is an essential component to evaluate in patients suspected of having a cerebellar disease. These activities correlate well with numerous lifelong meas…
  • StatPearls: Trinucleotide Repeat Disorders [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Ramakrishnan Sharanya S Grant Government Medical College and Sir JJ Group of Hospitals Gupta Vikas V South Carolina Department of Mental Health BOOK
  • Trinucleotide repeat disorders consist of a group of human diseases, which are a result of an abnormal expansion of repetitive sequences and primarily affect the nervous system. These occur during various stages of human development. Repetitive sequences, scattered in the microsatellite regions, usually account for about 30% of the human genome. In a normal person, the main purpose of various len…
  • StatPearls: Hartnup Disease [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Hashmi Mydah S. MS Army Medical College Gupta Vikas V South Carolina Department of Mental Health BOOK
  • Amino acids are building blocks for protein. There are three types of amino acids based on the polarity of the side chain. It includes acidic, basic, and neutral amino acids. Hartnup disease is an autosomal recessive inherited nutritional disorder due to decreased absorption of neutral amino acids from the gut and kidney. It has a wide range of clinical spectrum including neutral aminoaciduria, i…
  • StatPearls: Sensory Neuropathy [BOOK]
    . StatPearls Publishing: Treasure Island (FL) Gomatos Elias L. EL Westside Regional Medical Center Rehman Anis A Southern Illinois University BOOK
  • Sensory neuropathies refer to a host of diseases that result in loss of sensation throughout the body. Collectively, sensory neuropathies can result from a plethora of conditions that this review will discuss. These may further sub-divide into small fiber (pain-dominant) and large fiber (ataxia-predominant) pathologies. When classifying sensory neuropathy for appropriate treatment and management,…
  • Degron capability of the hydrophobic C-terminus of the polyglutamine disease protein, ataxin-3. [Journal Article]
    J Neurosci Res. 2020 Jul 09 [Online ahead of print]Blount JR, Johnson SL, … Tsou WL
  • Ataxin-3 is a deubiquitinase and polyglutamine disease protein whose cellular properties and functions are not entirely understood. Mutations in ataxin-3 cause spinocerebellar ataxia type 3 (SCA3), a neurodegenerative disorder that is a member of the polyglutamine family of diseases. Two major isoforms arise from alternative splicing of ATXN3 and are differently toxic in vivo as a result of faste…
  • Paradoxical Embolism in a Case of Hereditary Hemorrhagic Telangiectasia: Case Report with Literature Review. [Case Reports]
    Neurol India. 2020 May-Jun; 68(3):665-668.Baby N, Kunnathuparambil SG, … Kuriakose AM
  • Ischemic stroke involving multiple artery territory with normal vessels gives a clue for an embolic stroke. Paradoxical embolization is a recognized cause of ischemic stroke. We describe a 48-year-old male who presented with acute onset giddiness, mild dysarthria, right hemiparesis, and ataxia. Clinical examinations indicated left cerebellar signs with right hemiparesis. Additionally, the patient…
  • Long term follow up after transorbital penetrating injury: A case report. [Case Reports]
    Am J Ophthalmol Case Rep. 2020 Sep; 19:100792.Vloka C, Vloka A, … Stefko S
  • CONCLUSIONS: Our case illustrates the importance of such a longitudinal follow up. It demonstrates the possible severity of the sequelae from these types of injuries including chronic pain and gait ataxia, as well as EOM and autonomic dysfunction. Due to the potential ongoing needs of such patients, it is important to plan a long-term, team-based approach that centers around physical therapy and improving long term quality of life.
  • [Unilateral ptosis induced by pure midbrain infarction: a case report]. [Journal Article]
    Rinsho Shinkeigaku. 2020 Jul 07 [Online ahead of print]Nakamura Y, Kurauchi Y, … Shimohama S
  • We describe herein a case with left-side ptosis induced by pure midbrain infarction in a 49-year-old woman. She also presented with diplopia and right-side cerebellar ataxia. MRI demonstrated new ischemic stroke of the left ventral paramedian midbrain. In this case, ischemia of the left oculomotor fascicles caused the left-side ptosis and diplopia, and ischemia of the left decussation of the supe…
New Search Next