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2,586 results
  • Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome. [Randomized Controlled Trial]
  • NEJMN Engl J Med 2019 05 23; 380(21):1997-2008
  • National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Moss M, … Angus DC
  • CONCLUSIONS: Among patients with moderate-to-severe ARDS who were treated with a strategy involving a high PEEP, there was no significant difference in mortality at 90 days between patients who received an early and continuous cisatracurium infusion and those who were treated with a usual-care approach with lighter sedation targets. (Funded by the National Heart, Lung, and Blood Institute; ROSE number, NCT02509078.).
  • StatPearls: Cisatracurium [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Strawbridge Andrew D. AD San Antonio Uniformed Services HEC Hauser Joshua M. JM Brooke Army Medical Center
  • Cisatracurium besylate is an intermediate-acting, non-depolarizing neuromuscular blocking drug (NMBD). Cisatracurium has a benzylisoquinolinium structure and is the 1R cis-1’R cis isomer of atracuriu…
  • Resistance towards nondepolarising muscle relaxants: prolonged onset time: A systematic review. [Journal Article]
  • EJEur J Anaesthesiol 2019 Apr 03
  • Mørk EL, Kristensen ML, … Gätke MR
  • CONCLUSIONS: A prolonged onset time should be suspected in patients with thermal injury and Duchenne's muscular dystrophy. Further, evidence supports a prolonged onset time in patients with infection, oculopharyngeal muscular dystrophy, congenital heart defects, kidney failure, liver cirrhosis treated with ulinastatin along with remifentanil or intravenous fluids administered prior to NDMR.
  • Cerebral Oxygenation During Neonatal Intubation-Ancillary Study of the Prettineo-Study. [Journal Article]
  • FPFront Pediatr 2019; 7:40
  • Vedrenne-Cloquet M, Breinig S, … Durrmeyer X
  • CONCLUSIONS: Our results suggest a frequent decrease in cerebral oxygenation without obvious impairment in cerebral autoregulation during neonatal intubation with premedication. This study confirms the feasibility and the informative value of cerebral NIRS monitoring in this setting. Clinical Trial Registration:, identifier NCT02700893.
  • StatPearls: Pancuronium [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Das Gyan N. GN San Antonio Military Medical Center Maani Christopher V. CV US Army
  • Pancuronium bromide is a long-acting, bis-quaternary aminosteroid, non-depolarizing, neuromuscular blocking drug (NMBD) which was first synthesized in 1964 and was found to possess fewer adverse effe…
  • StatPearls: Neuromuscular Blockade [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Cook Danielle D UPMC Pinnacle Simons David J. DJ UPMC Lititz
  • Neuromuscular blockade is frequently used in anesthesia to facilitate endotracheal intubation, optimize surgical conditions, and assist with mechanical ventilation in patients who have reduced lung c…
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