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42,477 results
  • Choroidal Thickness Profiles and Associated Factors in Myopic Children. [Journal Article]
    Optom Vis Sci. 2023 Jan 01; 100(1):57-66.Kobia-Acquah E, Flitcroft DI, … Loughman J
  • CONCLUSIONS: Choroidal thickness was thinnest in the nasal macular region and varied systematically across all macular locations, with axial length and spherical equivalent refraction being the strongest determinants of ChT. Longitudinal evidence will need to evaluate whether any differences in ChT profiles are predictive of myopic progression and to determine the role of ChT measurements in identifying myopic children most in need of myopia control treatment.
  • Topical Review: Studies on Management of Myopia Progression from 2019 to 2021. [Journal Article]
    Optom Vis Sci. 2023 Jan 01; 100(1):23-30.Lanca C, Repka MX, Grzybowski A
  • CONCLUSIONS: Myopia is a common eye condition that increases the risk of sight-threatening complications. Each additional diopter increases the chance of complications. The purpose of this review was to make an overview of myopia control treatment options for children with myopia progression.In this nonsystematic review, we searched PubMed and Cochrane databases for English-language studies published from 2019 to September 2021. Emphasis was given to selection of randomized controlled trials. Nineteen randomized controlled trials and two retrospective studies were included. Topical atropine and orthokeratology remain the most used treatments, whereas lenses with novel designs are emerging treatments. Overall myopia progression in the treatment groups for low-dose atropine and orthokeratology was lower than in the control groups, and their efficacy was reported in several randomized controlled trials and confirmed by various systematic reviews and meta-analysis. The findings of myopia progression and axial elongation for the MiSight, defocus incorporated multiple segment spectacle lens, highly aspherical lenslets, and diffusion optics technology spectacle lens were comparable. Public health interventions to optimize environmental influences may also be important strategies to control myopia. Optimal choice of management of myopia depends on treatment availability, acceptability to child and parents, and specific patient features such as age, baseline myopia, and lifestyle. Eye care providers need to understand the advantages and disadvantages of each therapy to best counsel parents of children with myopia.
  • Bradyarrhythmia In A Marathonist: Cardiac Vagal Denervation As Alternative Treatment. [Journal Article]
    Rev Port Cardiol. 2023 Jan 21 [Online ahead of print]Neto M, Cavaco D, … Adragão P
  • Although not routinely used, cardioneuroablation or modulation of the cardiac autonomic nervous system has been proposed as an alternative approach to treat young individuals with enhanced vagal tone and significant atrioventricular (AV) disturbances.We report the case of a 42-year-old athlete with prolonged ventricular pauses associated with sinus bradycardia and paroxysmal episodes of AV block …
  • Water Drinking Behavior Associated with Aversive Arousal in Rats: An Integrative Approach. [Review]
    Brain Sci. 2022 Dec 29; 13(1)Brudzynski SM
  • Cholinergic muscarinic stimulation of vast areas of the limbic brain induced a well-documented polydipsia in laboratory rats. This excessive water-drinking behavior has not received any convincing biological and physiological interpretation for the last 50 years. This review offers such an interpretation and suggests that cholinergically induced drinking response, mostly by carbachol, is associat…
  • Paxlovid-Induced Symptomatic Bradycardia and Syncope. [Case Reports]
    Cureus. 2023 Jan; 15(1):e33831.Ganipisetti VM, Bollimunta P, Maringanti S
  • Paxlovid (nirmatrelvir/ritonavir) is a game changer in the fight against COVID-19 due to its ease of administration and significant benefits of reducing progression to severe COVID-19, hospitalization, and death. Cardiac adverse events such as bradycardia and syncope are not known with this medication. We report a case of a 71-year-old patient who developed symptomatic bradycardia, syncopal episo…
  • Suicidal attempt with eliglustat overdose. [Case Reports]
    JIMD Rep. 2023 Jan; 64(1):23-26.Nadler J, Hermanns-Clausen M, Dilger K
  • Eliglustat is an orphan medicine used for long-term treatment of Gaucher disease type 1 (GD1) in adults. GD1 is a genetic condition, in which glucosylceramide builds up in the body, typically in liver, spleen, and bone. Clinical signs and symptoms of the disease are anemia, tiredness, easy bruising, hepatosplenomegaly, bone pain, and fractures. Eliglustat works by blocking glucosylceramide syntha…
  • Transient asystole associated with vasovagal reflex in an oral surgery patient: A case report. [Case Reports]
    SAGE Open Med Case Rep. 2023; 11:2050313X221146019.Shimoda H, Yamauchi K, Takahashi T
  • The perioperative cardiac events may be brought about by a relative imbalance of autonomic activities due to excessive psychological and physical stress. The present case study focuses on the asystole that can occur as a serious cardiac adverse event associated with vasovagal reflex likely to be triggered by venipuncture for securing an intravenous line during dental care. In addition, we describ…
  • BRASH Syndrome Presenting With Idioventricular Escape Rhythm in a Patient With Trifascicular Block. [Case Reports]
    Cureus. 2022 Dec; 14(12):e32217.Aiwuyo HO, Ilerhunmwuwa NP, … Rafii SE
  • Bradycardia, renal failure, atrioventricular (AV) nodal disease, shock, and hyperkalemia (BRASH) syndrome is a well-recognized constellation of distinct clinicopathologic entities comprising bradycardia, renal failure, AV nodal disease, shock, and hyperkalemia. Our patient is an 89-year-old female with a past medical history significant for hypertension and diabetes, who was newly started on labe…
  • [A survey on the practice of bronchoscopy in county-level hospitals of China]. [Journal Article]
    Zhonghua Jie He He Hu Xi Za Zhi. 2023 Jan 12; 46(1):27-33.Wang FY, Tang CL, … Li SY
  • Objective: To investigate the bronchoscopy resource allocation and technology application in county-level hospitals in China. Methods: A cross-sectional survey was conducted. In 2021, 12 provinces were sampled from all provinces in China according to the regional Gross Domestic Product (GDP) and the number of counties, in which a total of 291 county-level hospitals were randomly enrolled. Two cou…
  • Survival in canine tetanus - retrospective analysis of 42 cases (2006-2020). [Journal Article]
    Front Vet Sci. 2022; 9:1015569.Zitzl J, Dyckers J, … Hazuchova K
  • CONCLUSIONS: Young dogs with a rapid course of severe generalized tetanus have a guarded prognosis. The previously described severity classification scheme proved valuable in predicting survival. Prospective multi-center studies are needed to clarify the prognostic significance of age, sedative usage and modified versions of an established classification scheme, including the presence of respiratory complications.
  • LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice. [Journal Article]
    Fundam Clin Pharmacol. 2022 Dec 29 [Online ahead of print]Noé JP, de Souza-Ferro JN, … Barreto E
  • In the present study, we examined the antinociceptive and anti-inflammatory activities of a guanylhydrazone derivative, (E)-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2-guanylhydrazone hydrochloride (LQM10), in mice. The antinociceptive effect was determined by assessing behavioural responses in different pain models, while anti-inflammatory activity was examined in carrageenan-induced pleurisy. In…
  • Changes in ocular biological parameters after cycloplegia based on dioptre, age and sex. [Journal Article]
    Sci Rep. 2022 12 28; 12(1):22470.Tao Y, Cheng X, … Ouyang J
  • The effects of cycloplegia on ocular biological parameters in children have been extensively studied, but few studies have compared these parameters between different refractive states, ages, and sexes. Therefore, the purpose of this study was to investigate the changes in ocular biometry before and after cycloplegia in different groups based on dioptre, age and sex. We examined a total of 2049 p…
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