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40,961 results
  • Islet adaptation in GIP receptor knockout mice. [Review]
    Peptides 2019; :170152Ahrén B, Yamada Y, Seino Y
  • Glucose-dependent insulinotropic polypeptide (GIP) receptor knockout (KO) mice are tools for studying GIP physiology. Previous results have demonstrated that these mice have impaired insulin response to oral glucose. In this study, we examined the insulin response to intravenous glucose by measuring glucose, insulin and C-peptide after intravenous glucose (0.35 g/kg) in 5-h fasted female GIP rece…
  • Intrinsic Adaptation of Shr Right Atrium Reduces Heart Rate. [Journal Article]
    J Cardiovasc Pharmacol 2019Dantas Rodrigues JQ, Camara H, … Jurkiewicz A
  • Hypertension represents an autonomic dysfunction, characterized by increased sympathetic and decreased parasympathetic cardiovascular tone leading to resting tachycardia. Therefore, studies assessing hypertension-associated changes in isolated cardiac tissues were conducted under electric field stimulation to stimulate the neurons. Herein we characterize the influence of the autonomic neurotransm…
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