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(autacoid autocoid)
39 results
  • Neuroprotectin D1 inhibits retinal ganglion cell death following axotomy. [Journal Article]
    Prostaglandins Leukot Essent Fatty Acids 2008; 79(6):201-7Qin Q, Patil KA, … Sharma SC
  • Neuroprotectin D1 (NPD1), a docosahexaenoic acid-derived autacoid, is an endogenous neuroprotective and anti-inflammatory mediator that is generated in the retina and brain. The effects of exogenous NPD1 on retinal ganglion cell (RGC) apoptosis and the role of 12/15-lipoxygenase (Alox15) in retina were evaluated after optic nerve transection (ONT). Treatment with NPD1 was associated with signific…
  • Cyclooxygenase enzymes: regulation and function. [Review]
    Curr Pharm Des 2004; 10(6):577-88Fitzpatrick FA
  • The cyclooxygenase isoenzymes, COX-1 and COX-2, catalyze the formation of prostaglandins, thromboxane, and levuloglandins. The prostaglandins are autocoid mediators that affect virtually all known physiological and pathological processes via their reversible interaction with G-protein coupled membrane receptors. The levuloglandins are a newer class of products that appear to act via irreversible,…
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