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47 results
  • Morbidity pattern and interferon gamma level in sickle cell anemia patients with autosplenectomy. [Journal Article]
  • NJNiger J Clin Pract 2018; 21(12):1615-1621
  • Okongwu CI, Fasola FA, … Onifade AA
  • CONCLUSIONS: This study showed a higher prevalence of infection and bone pain crisis among SCA patients with autosplenectomy than in SCA patients without autosplenectomy. It also showed comparable level of IFN-γ in the 2 groups of patients. Patients with autosplenectomy may benefit from early institution of drugs such as hydroxyurea to improve quality of life.
  • Inflammation in sickle cell disease. [Journal Article]
  • CHClin Hemorheol Microcirc 2018; 68(2-3):263-299
  • Conran N, Belcher JD
  • The primary β-globin gene mutation that causes sickle cell disease (SCD) has significant pathophysiological consequences that result in hemolytic events and the induction of the inflammatory processe…
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