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12,311 results
  • Live imaging the Foreign Body Response reveals how dampening inflammation reduces fibrosis. [Journal Article]
    J Cell Sci 2019Gurevich DB, French KE, … Martin P
  • Implanting biomaterials in tissues leads to inflammation and a Foreign Body Response (FBR), which can result in rejection. Here we live image the FBR triggered by surgical suture implantation in a translucent zebrafish model and compare with an acute wound response. We observe inflammation extending from the suture margins, and correlating with subsequent avascular and fibrotic encapsulation zone…
  • Nailfold videocapillaroscopy alterations in dermatomyositis, antisynthetase syndrome, overlap myositis, and immune-mediated necrotizing myopathy. [Journal Article]
    Clin Rheumatol 2019Soubrier C, Seguier J, … Schleinitz N
  • CONCLUSIONS: In this limited series of patients, we observed that DM and OM NVC abnormalities are different from ASS and IMNM. We could not determine NVC specific patterns associated with myositis-specific antibody subtypes of DM because of the small number of patients. Key Points • Nailfold videocapillaroscopy abnormalities are different in subgroups of inflammatory myopathies. • Giant capillaries, disorganization, and major capillary loss are observed in overlap myositis and dermatomyositis but not in antisynthetase syndrome (ASS) or immune-mediated necrotizing myopathy. • Nailfold videocapillaroscopy abnormalities in overlap myositis (with the exclusion of ASS) are close to systemic sclerosis.
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