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24,553 results
  • Anti-N-methyl-D-aspartate Receptor Autoimmune Encephalitis: A Case Report. [Journal Article]
    JNMA J Nepal Med Assoc. 2022 Nov 02; 60(255):962-964.Yadav B, Chaurasia D, … Dhungana K
  • Anti-N-methyl-D-aspartate receptor encephalitis is a form of autoimmune encephalitis with acute or subacute neuropsychiatric symptoms. Despite this fact, due to a couple of factors, this condition remains insufficiently acknowledged and is an under-recognised clinical scenario. We describe a case of a patient presenting with fever, headache and altered sensorium along with a history of disorienta…
  • Azathioprine Induced Pancytopenia in a Patient with Vogt-Koyanagi-Harada Disease: A Case Report. [Journal Article]
    JNMA J Nepal Med Assoc. 2022 Oct 01; 60(254):902-905.Khatri S, Khatri S, … Singh AK
  • Vogt-Koyanagi-Harada disease is a multisystem autoimmune inflammatory disorder that affects the eyes, ears, skin, and the nervous system. It is a rare disease that mainly affects Asian, Hispanic, and Middle Eastern populations. Systemic steroids and immunosuppressants are frequently used to treat autoimmune diseases like this. Despite the fact that they reduce morbidity, immunosuppressants can ha…
  • Risk factors for serious infections in ANCA-associated vasculitis. [Journal Article]
    Ann Rheum Dis. 2023 Jan 26 [Online ahead of print]Odler B, Riedl R, … RAVE−ITN Research Group
  • CONCLUSIONS: The use of low-dose TMP/SMX is associated with reduced risk of severe infections in patients with AAV treated with either RTX or CYC/AZA. Reduced B cell subpopulations at start of treatment might be a useful correlate of reduced immunocompetence.
  • Expert Consensus on the Systemic Treatment of Atopic Dermatitis in Special Populations. [Review]
    J Eur Acad Dermatol Venereol. 2023 Jan 25 [Online ahead of print]Adam DN, Gooderham MJ, … Yeung J
  • With the increasing number of options for the treatment of moderate-to-severe atopic dermatitis, clinicians need guidance on a practical approach to selecting a systemic agent for specific patient populations. We convened an expert panel consisting of 12 members to conduct a literature review and summarize relevant data related to six scenarios of clinical interest: comorbid asthma, ocular surfac…
  • Azathioprine-Induced Pancreatitis in a Patient With Systemic Lupus Erythematosus. [Case Reports]
    Cureus. 2022 Dec; 14(12):e32697.Ghazanfar H, Shin D, Ihimoyan A
  • Acute pancreatitis is an inflammatory disorder of the pancreas and a leading gastrointestinal cause of admission in the United States. The most common causes of acute pancreatitis are gallstones and alcohol. It is rarely caused by medications. Azathioprine-induced pancreatitis is rare and is more common in patients with Crohn's Disease. In this case report, we present a rare case of azathioprine-…
  • Therapeutic Management of Adults with Inflammatory Bowel Disease and Malignancies: A Clinical Challenge. [Review]
    Cancers (Basel). 2023 Jan 16; 15(2)Ferretti F, Cannatelli R, … Ardizzone S
  • Patients with chronic inflammatory bowel diseases (IBD) have increased risk of developing intestinal and extraintestinal cancers. However, once a diagnosis of malignancy is made, the therapeutic management of Crohn's disease (CD) and ulcerative colitis (UC) can be challenging as major guidelines suggest discontinuing the ongoing immunosuppressant and biological therapies for at least 2-5 years af…
  • Renal disease in sarcoidosis patients in a German multicentric retrospective cohort study. [Journal Article]
    Respir Med. 2023 Jan 17 [Online ahead of print]Bergner R, Weiner SM, … Korsten P
  • CONCLUSIONS: Our data of the largest cohort with biopsy-confirmed renal sarcoidosis demonstrate a higher prevalence (27.5% of all patients) than previously published with a relevant disease burden. The urinary findings in most cases were only mildly abnormal, and some patients did not have renal biopsy despite abnormal urinary results. A renal workup should be performed in all patients with a new diagnosis of sarcoidosis.
  • Systematic Review of therapies for refractory ulcerative proctitis. [Review]
    J Gastroenterol Hepatol. 2023 Jan 16 [Online ahead of print]Raja SS, Bryant RV, … Rayner CK
  • CONCLUSIONS: Refractory UP remains a neglected entity, with a dearth of prospective clinical trials to guide therapeutic decision-making. Current evidence supports a role for topically administered tacrolimus.
  • Synchronous Presentation of Autoimmune Hepatitis and Multiple Myeloma. [Case Reports]
    J Hematol. 2022 Dec; 11(6):216-222.Yohannan B, Omo-Ogboi AC, … Rios A
  • Autoimmune hepatitis (AIH) is a rare immune-mediated disease predominantly seen in women and triggered by various environmental factors. Rarely, AIH can be triggered by an underlying malignancy. We report a woman in her 60s who presented with markedly abnormal liver biochemical tests. Serology was positive for anti-smooth muscle antibodies and a liver biopsy confirmed AIH. During the hospital cou…
  • Development of a Patient Decision Aid to Help People Living with Inflammatory Bowel Disease. [Journal Article]
    Middle East J Dig Dis. 2022 Jan; 14(1):57-63.Tamizifar B, Ehsani M, … Moladoost A
  • BACKGROUND: Patient decision aid (PDA) is a tool, which helps the improvement of shared decisionmaking and is a part of the paradigm shift from physician-centered decisions to patient-centered shared decision making. In this study, we aimed to describe the process used to develop a PDA for facilitating shared decision-making about treatment in patients with inflammatory bowel disease (IBD) who ne…
  • Efficacy of Infliximab for the Treatment of Oral Manifestation of Crohn's Disease. [Case Reports]
    Case Rep Gastroenterol. 2022 Sep-Dec; 16(3):629-636.Aginbay A, Khamzina S, … Kulkayeva G
  • Oral manifestations of IBD can be specific or nonspecific, due to intestinal malabsorption or induced by pharmacological treatments. Oral manifestations may precede the diagnosis of IBD or interfere with timely diagnosis and treatment. The paradigm of treatment for oral lesions in patients with IBD is based on treating and controlling the intestinal manifestations of the underlying disease as wel…
  • Successful long-term treatment of paediatric ulcerative colitis with vedolizumab: a case report. [Journal Article]
    Eur J Hosp Pharm. 2022 Dec 09 [Online ahead of print]Codina-Jiménez C, Bosch Peligero M, … Quiñones C
  • Biologics are recommended to treat paediatric ulcerative colitis (UC) that is chronically active or steroid-dependent despite aminosalicylic acids (5-ASA) and thiopurine treatments. Anti-tumour necrosis factor inhibitors (Anti-TNF inhibitors) are the agents of choice and vedolizumab could be considered as second-line biologic therapy.In the current case, we aim to describe a successful long-term …
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