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8,717 results
  • Fast biofilm penetration and anti-PAO1 activity of nebulized azythromicin in nanoarchaeosomes. [Journal Article]
    Mol Pharm 2019Altube MJ, Martinez MM, … Romero EL
  • Azithromycin (AZ) is a broad-spectrum antibiotic with anti-inflammatory and anti-quorum sensing activity against biofilm forming bacteria such as Pseudomonas aeruginosa (Pa). AZ administered by oral or parenteral routes however, neither efficiently access nor remain in therapeutic doses inside pulmonary biofilm depths. Instead, inhaled nanocarriers loaded with AZ may revert the problem of low acc…
  • Successful systemic and topical treatment of Mycobacterium abscessus otomastoiditis. [Journal Article]
    Antimicrob Agents Chemother 2019van Wijk F, Waterval J, … van Ingen J
  • Mycobacterium abscessus is an extensively drug-resistant opportunistic pathogen that can cause chronic otomastoiditis. There are no evidence-based treatment regimens for this severe infection. We treated four children with M. abscessus otomastoiditis with a structured regimen of topical imipenem and tigecycline, intravenous imipenem and tigecycline and oral clofazimine and azithromycin and adjunc…
  • Drug-Resistant Salmonella typhi in Pakistan. [Journal Article]
    Clin Pediatr (Phila) 2019; :9922819881203Petrin CE, Steele RW, … Wright A
  • Enteric fever (formerly typhoid fever) is a bacterial illness caused by fecal-oral transmission of Salmonella typhi or paratyphi. In early 2018, an outbreak of Salmonella typhi resistant to third-generation cephalosporins, ampicillin, ciprofloxacin, trimethroprim-sulfamethoxazole, and chloramphenicol was reported in Pakistan. This strain, termed "extensively resistant typhi," has infected more th…
  • Detection and determination of stability of the antibiotic residues in cow's milk. [Journal Article]
    PLoS One 2019; 14(10):e0223475Kurjogi M, Issa Mohammad YH, … Jogaiah S
  • In the present study, antibiotic residues were detected in milk samples collected from the dairy herds located in Karnataka, India, by microbiological assay. Subsequently, the detected antibiotics were identified as azithromycin and tetracycline, by high-performance liquid chromatography, further both the antibiotics detected in the cow milk samples were found to be at high concentration (9708.7 …
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