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24 results
  • Parenteral Administration of Capsule Depolymerase EnvD Prevents Lethal Inhalation Anthrax Infection. [Journal Article]
    Antimicrob Agents Chemother 2015; 59(12):7687-92Negus D, Vipond J, … Taylor PW
  • Left untreated, inhalation anthrax is usually fatal. Vegetative forms of Bacillus anthracis survive in blood and tissues during infection due to elaboration of a protective poly-γ-D-glutamic acid (PDGA) capsule that permits uncontrolled bacterial growth in vivo, eventually leading to overwhelming bacillosis and death. As a measure to counter threats from multidrug-resistant strains, we are evalua…
  • Research on tuberculosis: 75 years of IBIT contributions. [Historical Article]
    Braz J Infect Dis 2013 Mar-Apr; 17(2):205-10Leite G
  • In 1937, the foundation year of the Brazilian Institute for Tuberculosis Research, three questions persisted in the researchers' mind: "What is the real value of BCG? How to solve the problem of the chest register of large communities? When will we have a specific drug for the treatment of tuberculosis?" Along with this line of thought, the author presents a list of the Institute's main contribut…
  • Integration of pharmacokinetic and pharmacodynamic indices of marbofloxacin in turkeys. [Journal Article]
    Antimicrob Agents Chemother 2006; 50(11):3779-85Haritova AM, Rusenova NV, … Fink-Gremmels J
  • Fluoroquinolones are extensively used in the treatment of systemic bacterial infections in poultry, including systemic Escherichia coli bacillosis, which is a common disease in turkey flocks. Marbofloxacin has been licensed for use in various mammalian species, but not as yet for turkeys, although its kinetic properties distinguish it from other fluoroquinolones. For example, the longer half-life…
  • Perspectives on Shiga-like Toxin Infections in Argentina †. [Journal Article]
    J Food Prot 1997; 60(11):1458-1462López EL, Contrini MM, … Cleary TG
  • Argentina has the highest frequency of hemolytic uremic syndrome (HUS) in the world (300 cases/year). The risk of HUS in children from 6 to 48 months old is approximately 22/100,000 in Buenos Aires. In Argentina, HUS is the most frequent cause of acute renal damage and the second cause of chronic renal injury in children. We have shown that during the spring/summer season, the incidence of Shiga-…
  • [Problems of resistance (author's transl)]. [Journal Article]
    Tijdschr Diergeneeskd 1975; 100(5):270-3Overgoor GH
  • The results of sensitivity tests performed during the period from 1970 up to 1973 inclusive are compared with those obtained in pervious years. This showed that resistance to penicillin had increased in staphylococci causing bovine mastitis. During each single year, however, there was a decrease. S. typhimurium isolated from cattle showed increased resistance to chloramphenicol, neomycin and ampi…
  • Enteropathogenicity of Escherichia coli. I. Evaluation of mouse intestinal loops. [Journal Article]
    Infect Immun 1971; 4(4):473-8Punyashthiti K, Finkelstein RA
  • A ligated mouse intestinal loop assay has been introduced to evaluate the enteropathogenicity of strains of Escherichia coli. When inoculated as whole cultures, 19 (34%) of 55 strains isolated from diarrheic infants, each of 4 strains associated with diarrhea in human adults, and 5 of 7 strains associated with porcine coli bacillosis were found capable of causing fluid accumulation in this model.…
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