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5,421 results
  • Calcium phosphate nanoparticles as intrinsic inorganic antimicrobials: mechanism of action. [Journal Article]
    Biomed Mater. 2020 Jul 03 [Online ahead of print]Wu VM, Huynh E, … Uskokovic V
  • This is the final report of the study aimed at assessing the antimicrobial activity of CP nanoparticles delivered in the form of hydroxyapatite (HAp) or amorphous CP (ACP) and understanding the fundamental principles behind their mechanisms of action. Not responding to propidium iodide and causing no gross morphological changes except moderate stress-induced filamentation in E. coli, CP nanoparti…
  • Role of Apis cerana cerana N-terminal asparagine amidohydrolase (AccNtan1) in oxidative stress. [Journal Article]
    J Biochem. 2020 Jul 02 [Online ahead of print]Zhao G, Wang C, … Guo X
  • N-Terminal asparagine amidohydrolase (Ntan1) is a component of the ubiquitin-dependent N-end rule pathway of protein degradation that has been implicated in a variety of physiological functions, including the sensing of heme, oxygen, nitric oxide, selective elimination of misfolded proteins and the repair of DNA. We identified the AccNtan1 gene from Apis cerana cerana and investigated its role in…
  • Bacteriostatic and bactericidal clays: an overview. [Review]
    Environ Geochem Health. 2020 Jun 30 [Online ahead of print]Gomes CF, Gomes JH, da Silva EF
  • This article aims to draw an overview on the actual knowledge on bacteriostatic and bactericidal natural clays. Particular emphasis is given to the role of clay itself, the action of reduced metals located either in the structure of clay minerals or external to them as constituents of associate minerals, and the definition of the mechanisms of action based on the achievements found in all availab…
  • Anaerobic digestion of mercury phytoextraction crops with intermediary stage bio-waste polymer treatment. [Journal Article]
    Int J Phytoremediation. 2020 Jun 30 [Online ahead of print]Rollinson AN, Bhuptani J, … Radu T
  • In laboratory experiments, Lepidium sativum L. and Mentha spicata L. were grown in compost spiked with mercury. After cultivation for 20 and 68 days, respectively, translocation factors of 0.05 ≤ TF ≤ 0.2 (Lepidium sativum) and accumulation factors of 2.2 ≤ AF ≤ 12 (Mentha spicata) were recorded. Plants were then harvested and used as feedstock for bench-scale anaerobic digesters. The reactors op…
  • Electrochemical modification of the Ti-15Mo alloy surface in solutions containing ZnO and Zn3(PO4)2 particles. [Journal Article]
    Mater Sci Eng C Mater Biol Appl. 2020 Oct; 115:111098.Leśniak-Ziółkowska K, Kazek-Kęsik A, … Simka W
  • This paper reports on the plasma electrolytic oxidation (PEO) of titanium alloy Ti-15Mo in baths containing zinc to obtain biomaterials with bacteriostatic and antibacterial properties. The Ti-15Mo surface was oxidised in a 0.1 M Ca(H2PO2)2 bath containing zinc compound particles: ZnO or Zn3(PO4)2. During the PEO process, the applied voltage was 300 V, and the current density was 150 mA∙cm-2. The…
  • In vitro comparisons of microscale and nanoscale calcium silicate particles. [Journal Article]
    J Mater Chem B. 2020 Jun 29 [Online ahead of print]Huang YR, Wu IT, … Ding SJ
  • Calcium silicate (CaSi) materials have been used for bone repair and generation due to their osteogenic properties. Tailoring the surface chemistry and structure of CaSi can enhance its clinical performance. There is no direct comparison between microscale and nanoscale CaSi particles. Therefore, this article aimed to compare and evaluate the surface chemistry, structure, and in vitro properties …
  • Antibacterial and antibiofilm activities of Trollius altaicus C. A. Mey. On Streptococcus mutans. [Journal Article]
    Microb Pathog. 2020 Jun 23 [Online ahead of print]Yan L, Wu W, Tian S
  • Dental caries is a chronic bacterial infectious disease caused by multiple factors, with Streptococcus mutans (S. mutans) as the main cariogenic bacteria. Trollius altaicus C. A. Mey. (TA) is a common folk medicine in the Xinjiang area of China. In this study, we investigated the inhibitory effect of T. altaicus C. A. Mey. (TA) flower extracts on S. mutans. The inhibition zone, minimum inhibitory…
  • Identification of antibacterial substances of Lactobacillus plantarum DY-6 for bacteriostatic action. [Journal Article]
    Food Sci Nutr. 2020 Jun; 8(6):2854-2863.Mao Y, Zhang X, Xu Z
  • The antimicrobial activity of lactic acid bacteria is closely related to its metabolites. Our results showed that Lactobacillus plantarum DY-6 had the highest antibacterial activities among the seven bacteria tested in this study. To fully understand the active antimicrobial substances in L. plantarum DY-6, the cell-free supernatant (CFS) were analyzed. Our data indicated that the antibacterial e…
  • A Physiological Basis for Nonheritable Antibiotic Resistance. [Review]
    mBio. 2020 Jun 16; 11(3)Pontes MH, Groisman EA
  • Antibiotics constitute one of the cornerstones of modern medicine. However, individuals may succumb to a bacterial infection if a pathogen survives exposure to antibiotics. The ability of bacteria to survive bactericidal antibiotics results from genetic changes in the preexisting bacterial genome, from the acquisition of genes from other organisms, and from nonheritable phenomena that give rise t…
  • In Vitro Biological Impact of Nanocellulose Fibers on Human Gut Bacteria and Gastrointestinal Cells. [Journal Article]
    Nanomaterials (Basel). 2020 Jun 12; 10(6)Lopes VR, Strømme M, Ferraz N
  • Wood-derived nanofibrillated cellulose (NFC) has long been recognized as a valuable nanomaterial for food-related applications. However, the safety of NFC cannot be predicted just from the chemical nature of cellulose, and there is a need to establish the effect of the nanofibers on the gastrointestinal tract, to reassure the safe use of NFC in food-related products. The present work selected the…
  • Exploring the phytochemical and nutraceutical potentials of dasapatrachurnam. [Journal Article]
    J Complement Integr Med. 2020 Jun 11 [Online ahead of print]Nadella R, Hernandez-Baltazar D, … Martinez-Fong D
  • BackgroundDasapatrachurnam (DPC), a multicurative powder prepared from the leaves of 10 green leafy vegetables, was developed recently with known ethnobotanical and ethnopharmacological significance. However, its functional role in curing a disease is not yet scientifically proven. The present study aims at performing the phytochemical screening of DPC and exploring its possible activity as bacte…
  • Immunomodulation by macrolides: therapeutic potential for critical care. [Review]
    Lancet Respir Med. 2020 Jun; 8(6):619-630.Reijnders TDY, Saris A, … van der Poll T
  • Critical illness is associated with immune dysregulation, characterised by concurrent hyperinflammation and immune suppression. Hyperinflammation can result in collateral tissue damage and organ failure, whereas immune suppression has been implicated in susceptibility to secondary infections and reactivation of latent viruses. Macrolides are a class of bacteriostatic antibiotics that are used in …
  • Effect of essential oils on pathogenic and biofilm-forming Vibrio parahaemolyticus strains. [Journal Article]
    Biofouling. 2020 Jun 09 [Online ahead of print]Mizan MFR, Ashrafudoulla M, … Ha SD
  • In this study, the effect of three essential oils (EOs) - clove oil (CO), thyme oil (TO), and garlic oil (GO), which are generally recognized as safe - on the planktonic growth, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), motility, biofilm formation, and quorum sensing (QS) of Vibrio parahaemolyticus was investigated. All three EOs showed bacteriostatic activ…
  • Clinical efficacy and the antimicrobial potential of silver formulations in arresting dental caries: a systematic review. [Journal Article]
    BMC Oral Health. 2020 Jun 03; 20(1):160.Fakhruddin KS, Egusa H, … Samaranayake LP
  • CONCLUSIONS: Taken together, in vitro evidence indicates the promising antimicrobial potential of silver-based formulations (SDF and nanosilver) against the predominant cariogenic flora, particularly from dentine lesions. Post-treatment clinical data of either the bactericidal and bacteriostatic effects of SDF or nanosilver are sparse. Furthermore, the current understanding of the specific size, concentration, antimicrobial mechanisms, and toxicological aspects of nano-silver compounds is inadequate to draw firm conclusions on their clinical utility.
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