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126 results
  • Modern use of 5-aminosalicylic acid compounds for ulcerative colitis. [Journal Article]
    Expert Opin Biol Ther 2019; :1-16Le Berre C, Roda G, … Peyrin-Biroulet L
  • Introduction: For 30 years, 5-aminosalicylic acid (5-ASA) has been the backbone of therapeutic management in patients with ulcerative colitis (UC). In the biologic era, it still remains the treatment of choice in mild-to-moderate UC. Positioning of this therapeutic class in moderate-to-severe UC is less clear. Areas covered: Several studies demonstrated the ability of 5-ASA to induce endoscopic r…
  • Drugs and Lactation Database (LactMed): Balsalazide [BOOK]
    National Library of Medicine (US): Bethesda (MD)BOOK
  • Although no information exists on the excretion of balsalazide into breastmilk, it is metabolized to the active drug mesalamine. A few cases of diarrhea have been reported in infants exposed to mesalamine, although the rate is not high. Most experts consider mesalamine derivatives to be safe during breastfeeding.[1][2][3][4] If balsalazide is required by the mother, it is not a reason to disconti…
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