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10,804 results
  • Vagal Afferent Processing by the Paratrigeminal Nucleus. [Review]
    Front Physiol 2019; 10:1110Driessen AK
  • The paratrigeminal nucleus is an obscure region in the dorsal lateral medulla, which has been best characterized as a collection of interstitial cells located in the dorsal tip of the spinal trigeminal tract. The paratrigeminal nucleus receives afferent input from the vagus, trigeminal, spinal, and glossopharyngeal nerves, which contribute to its long-known roles in the baroreceptor reflex and no…
  • Autonomic Abnormalities in Patients With Primary Sjogren's Syndrome - Preliminary Results. [Journal Article]
    Front Physiol 2019; 10:1104Brunetta E, Shiffer D, … Furlan R
  • Primary Sjögren's syndrome (pSS) is an autoimmune disease affecting exocrine glands and extra-glandular organs. There are conflicting reports on the presence of autonomic dysfunction in pSS and no data are available on the functional status of sympathetic outflow to the vessels and baroreceptor [baroreflex sensitivity (BRS)] control mechanisms. We investigated the cardiac (cBRS) and sympathetic (…
  • Force Sensing by Piezo Channels in Cardiovascular Health and Disease. [Journal Article]
    Arterioscler Thromb Vasc Biol 2019; :ATVBAHA119313348Beech DJ, Kalli AC
  • Mechanical forces are fundamental in cardiovascular biology, and deciphering the mechanisms by which they act remains a testing frontier in cardiovascular research. Here, we raise awareness of 2 recently discovered proteins, Piezo1 and Piezo2, which assemble as transmembrane triskelions to combine exquisite force sensing with regulated calcium influx. There is emerging evidence for their importan…
  • Cardiac and Vascular Sympathetic Baroreflex Control during Orthostatic Pre-Syncope. [Journal Article]
    J Clin Med 2019; 8(9)Furlan R, Heusser K, … Barbic F
  • We hypothesized that sympathetic baroreflex mediated uncoupling between neural sympathetic discharge pattern and arterial pressure (AP) fluctuations at 0.1 Hz during baroreceptor unloading might promote orthostatic pre-syncope. Ten volunteers (32 ± 6 years) underwent electrocardiogram, beat-to-beat AP, respiratory activity and muscle sympathetic nerve activity (MSNA) recordings while supine (REST…
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